Associations of work hours, job strain, and occupation with endothelial function: the Multi-Ethnic Study of Atherosclerosis (MESA)

Details

• Personal Author:
  Andrew, Michael E. ; Baron, Sherry L. ; Burchfiel CM ; Charles LE ; Diez Roux AV ; Fekedulegn D ; Foy CG ; Fujishiro K ; Kaufman JD ; Landsbergis P ; Stukovsky KH
• Description:
  Objective: To investigate associations of work hours, job control, job demands, job strain, and occupational category with brachial artery flow-mediated dilation (FMD) in 1499 Multi-Ethnic Study of Atherosclerosis participants. Methods: Flow-mediated dilation was obtained using high-resolution ultrasound. Mean values of FMD were examined across categories of occupation, work hours, and the other exposures using regression analyses. Results: Occupational category was significantly associated with FMD overall, with blue-collar workers showing the lowest mean values-management/professional = 4.97 +/- 0.22%; sales/office = 5.19 +/- 0.28%; services = 4.73 +/- 0.29%; and blue-collar workers = 4.01 +/- 0.26% (adjusted P < 0.001). There was evidence of effect modification by sex (interaction P = 0.031)-significant associations were observed among women (adjusted P = 0.002) and nearly significant results among men (adjusted P = 0.087). Other exposures were not significantly associated with FMD. Conclusions: Differences in endothelial function may account for some of the variation in cardiovascular disease across occupational groups. [Description provided by NIOSH]
• Subjects:
  Cardiovascular Diseases Cardiovascular System Demography Epidemiology Men Occupational Health Safety Women
• Keywords:
  Cardiovascular-disease Cardiovascular-function Cardiovascular-system-disease Cardiovascular-system-disorders Demographic-characteristics Exposure-levels Humans Statistical-analysis Surveillance-programs Ultrasound Work-intervals

  More +
• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Michigan ; New York ; North Carolina ; Ohio ; OSHA Region 10 ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; Pennsylvania ; Washington ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division ; DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  56
• Issue:
  11
• NIOSHTIC Number:
  nn:20045336
• Citation:
  J Occup Environ Med 2014 Nov; 56(11):1153-1160
• Contact Point Address:
  Luenda E. Charles, PhD, MPH, Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, HELD/BEB, MS L-4050, 1095 Willowdale Rd, Morgantown, WV 26505
• Email:
  lcharles@cdc.gov
• Federal Fiscal Year:
  2015
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:5455ede3781f66a4402bc5d6dd81e206e512937527fc7762c2a6ab7bf0a240d6417ceda0f00a22ad4e890ceeef014441916b1c92a4b82581f16c98b04c699904
• Download URL:
  https://stacks.cdc.gov/view/cdc/200793/cdc_200793_DS1.pdf
• File Type:
  [PDF - 127.82 KB ]