Work schedules and 11-year progression of carotid atherosclerosis in middle-aged Finnish men
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2015/01/01
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Description:OBJECTIVES: This study investigated the relationship between different work schedules and progression of carotid atherosclerosis, an early indicator of cardiovascular disease (CVD). METHODS: We studied 621 men, aged 42-60 years, in the prospective Kuopio Ischemic Heart Disease Risk Factor Study cohort. Using multivariable regressions adjusting for 22 covariates including total time worked during follow-up, we evaluated the associations of baseline work schedules with 11-year progression of ultrasonographically assessed carotid intima-media thickness (IMT), and their variation by preexisting CVD. RESULTS: Standard daytime work, weekend shifts, and evening/night/rotating shifts were associated with 31%, 37%, and 33% increases in IMT, respectively. Compared to daytime workers, weekend workers experienced a faster progression of carotid atherosclerosis [relative change ratio (RCR)=1.05, 95% CI: 1.00-1.09)]. This ratio was higher among men who had preexisting CVD. CONCLUSIONS: Weekend shifts, more than standard daytime work, appear to accelerate carotid atherosclerosis progression among middle-aged Finnish men, especially those with pre-existing CVD. [Description provided by NIOSH]
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ISSN:0271-3586
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Pages in Document:1-13
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Volume:58
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Issue:1
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NIOSHTIC Number:nn:20045296
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Citation:Am J Ind Med 2015 Jan; 58(1):1-13
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Contact Point Address:Niklas Krause, MD, PhD, Department of Environmental Health Sciences and Department of Epidemiology, The Fielding School of Public Health, UCLA, Box 95-1772; 56-071CHS, 650 Charles E.Young Drive South,Los Angeles,CA 90095-1772
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Email:niklaskrause@ucla.edu
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Federal Fiscal Year:2015
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Performing Organization:University of California Los Angeles
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Peer Reviewed:True
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Start Date:20050701
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Source Full Name:American Journal of Industrial Medicine
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End Date:20270630
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Main Document Checksum:urn:sha-512:79140bfee4ccd18bf96285a269a4685c465702c7bd889e8e563f32e95a49c2e7b8811e50e3c495fa90f77117a85ecc7fa1a010064c57f255fa28484bec6cd752
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