Energy-independent factors influencing noise-induced hearing loss in the chinchilla model

Details

• Personal Author:
  Hamernik RP ; Qiu W
• Description:
  The effects on hearing and the sensory cell population of four continuous, non-Gaussian noise exposures each having an A-weighted L(eq)=100 dB SPL were compared to the effects of an energy-equivalent Gaussian noise. The non-Gaussian noise conditions were characterized by the statistical metric, kurtosis (beta), computed on the unfiltered, beta(t), and the filtered, beta(f), time-domain signals. The chinchilla (n=58) was used as the animal model. Hearing thresholds were estimated using auditory-evoked potentials (AEP) recorded from the inferior colliculus and sensory cell populations were obtained from surface preparation histology. Despite equivalent exposure energies, the four non-Gaussian conditions produced considerably greater hearing and sensory cell loss than did the Gaussian condition. The magnitude of this excess trauma produced by the non-Gaussian noise was dependent on the frequency content, but not on the average energy content of the impacts which gave the noise its non-Gaussian character. These results indicate that beta(t) is an appropriate index of the increased hazard of exposure to non-Gaussian noises and that beta(f) may be useful in the prediction of the place-specific additional outer hair cell loss produced by non-Gaussian exposures. The results also suggest that energy-based metrics, while necessary for the prediction of noise-induced hearing loss, are not sufficient. [Description provided by NIOSH]
• Subjects:
  Animals Environmental Exposure Hearing Loss Laboratories Noise Noise, Occupational Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Auditory-system Environmental-exposure Etiology Exposure-limits Hearing-loss Laboratory-animals Noise-exposure Risk-factors Sound Statistical-analysis Workers

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• ISSN:
  0001-4966
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  110
• Issue:
  6
• NIOSHTIC Number:
  nn:20045081
• Citation:
  J Acoust Soc Am 2001 Dec; 110(6):3163-3168
• Contact Point Address:
  Roger P. Hamernik, Auditory Research Laboratory, State University of New York, Plattsburgh 12901
• Email:
  roger.hamernik@plattsburgh.edu
• Federal Fiscal Year:
  2002
• Performing Organization:
  Plattsburgh State University, New York
• Peer Reviewed:
  True
• Start Date:
  19860301
• Source Full Name:
  Journal of the Acoustical Society of America
• End Date:
  20130514
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e1d8cc28057ecd10553cf3f924b29cf8b4a224df8b67c6578cd734a61ee997939d1a111f805a4fb308e615a2a9d94c7794c7719a3fffaf88416b1839fe27cd4f
• Download URL:
  https://stacks.cdc.gov/view/cdc/200613/cdc_200613_DS1.pdf
• File Type:
  [PDF - 157.58 KB ]