Work hours, job strain, and occupation with endothelial function: the Multi-Ethnic Study of Atherosclerosis (MESA)

Details

• Personal Author:
  Andrew M ; Baron, Sherry L. ; Burchfiel C ; Charles L ; Diez Roux A ; Fekedulegn D ; Foy C ; Fujishiro K ; Kaufman J ; Landsbergis P ; Stukovsky SH
• Description:
  Objectives: To investigate associations of work hours, job control, job demands, job strain, and occupational category with endothelial function, a predictor of cardiovascular disease (CVD). Method: Currently employed participants free of CVD (n = 1499; 55.5% men; 62% non-white) of the Multi-Ethnic Study of Atherosclerosis provided information on work hours, job decision latitude, and job demands. Responses to current occupation were coded using the Census 2000 Occupational Codes; codes were collapsed to provide four occupational categories. Brachial artery flow-mediated dilation (FMD), a validated measure of endothelial function, was obtained using high-resolution ultrasound. Mean values of FMD, expressed as percent change in brachial artery diameter, were examined across categories of work hours (<40, 40, 41.49, .50) and the other exposures using ANOVA/ANCOVA. Results: Occupational category was significantly associated with FMD overall, with Blue-collar workers showing the lowest mean values after adjustment for age, gender, race/ethnicity, education, waist circumference, total and HDL cholesterol, body mass index, systolic and diastolic blood pressure, physical activity, smoking status, and pack-years of smoking: Management/Professional = 4.96 +/- 0.22%; Sales/Office = 5.06 +/- 0.27%; Services = 4.70 +/- 0.29%; Blue-collar workers = 4.18 +/- 0.27% (adjusted p = 0.001). There was evidence of effect modification between occupational category and FMD by gender (p = 0.031) such that in stratified analyses, significant associations were observed among women (adjusted p = 0.002) but not men (adjusted p = 0.098). None of the other work exposures were significantly associated with FMD. Conclusions: Blue-collar workers had decreased endothelial function compared to other workers; potential reasons should be examined in future studies. Decreased endothelial function may reflect a biological mechanism explaining occupational differences in CVD. [Description provided by NIOSH]
• Subjects:
  Aging Behavior Blood Body Weight Cardiovascular Diseases Cardiovascular System Demography Education Men Occupational Health Race Factors Safety Smokers Stress, Psychological Women Workplace

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• Keywords:
  Age-groups Analytical-processes Blood-pressure Body-weight Cardiovascular-disease Demographic-characteristics Humans Job-stress Occupations Physical-fitness Physiological-factors Racial-factors Smoking Sociological-factors Statistical-analysis Surveillance-programs Ultrasound Work-environment Workers

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• ISSN:
  1351-0711
• Document Type:
  Text
• Genre:
  Abstract or Summary
• Place as Subject:
  Illinois ; Michigan ; New York ; North Carolina ; Ohio ; OSHA Region 10 ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; Washington ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division ; DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  71
• NIOSHTIC Number:
  nn:20044608
• Citation:
  Occup Environ Med 2014 Jun; 71(Suppl 1):A73
• Federal Fiscal Year:
  2014
• Peer Reviewed:
  False
• Source Full Name:
  Occupational and Environmental Medicine. Challenges for Occupational Epidemiology in the 21st Century, EPICOH 2014, June 24-27, 2014, Chicago, Illinois
• Supplement:
  1
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d5a13b7cff69acbb07a657cb4d2d92e7510b31371beb81d3a6fc2d219aca66473ef7b764dc77dee87a40e9d2605868ec66afe083cc56651f3ff4c9f53710804f
• Download URL:
  https://stacks.cdc.gov/view/cdc/200275/cdc_200275_DS1.pdf
• File Type:
  [PDF - 67.20 KB ]