Urinary Reproductive Hormone Level Differences Between African American and Caucasian Women of Reproductive Age

Details

• Personal Author:
  Kesner JS ; Knecht EA ; Krieg EF Jr. ; LeMasters GK ; Lockey, James E. ; Reutman SR ; Shukla R
• Description:
  To compare urinary levels of reproductive hormones in African American and Caucasian women. Cross-sectional study. Ten United States Air Force (USAF) bases. African American (n = 33) and Caucasian (n = 65) women of reproductive age from a larger study of USAF women (n = 170). None. Urinary endocrine end points: follicular luteinizing hormone (LH), preovulatory LH, level of LH surge peak, early follicular follicle stimulating hormone (FSH), follicular LH:FSH ratio, midluteal FSH, FSH rise before menses, early follicular estrone 3-glucuronide (E(1)3G), midfollicular E(1)3G, periovulatory E(1)3G peak, midluteal E(1)3G, early follicular pregnanediol 3-glucuronide (Pd3G), follicular Pd3G, rate of periovulatory Pd3G increase, E(1)3G:Pd3G on the day of luteal transition, slope of E(1)3G:Pd3G, and midluteal Pd3G. Relative to Caucasians, African American women had significantly lower follicular phase LH:FSH ratios (mean +/- SD: 0.7 +/- 0.4 vs. 1.0 +/- 0.6), lower follicular phase Pd3G levels (1.0 +/- 0.5 vs. 1.2 +/- 0.8 microg/mg creatinine), and lower rates of periovulatory Pd3G increase (0.5 +/- 0.7 vs. 1.0 +/- 1.2 microg/mg creatinine). Findings of this analysis should be considered preliminary evidence of racial differences in hormone levels. Future studies are needed to determine whether these differences have clinical significance. [Description provided by NIOSH]
• Subjects:
  Endocrine System Epidemiology Estrogens Occupational Health Race Factors Safety Urine Urogenital System
• Keywords:
  African Americans Author Keywords: Hormones Caucasians Endocrine-system Estrogen Estrogenic-hormones Follicle Stimulating Hormone Hormone-activity Hormones Luteinizing Hormone Military-personnel Progesterone Racial-factors Racial Differences Reproduction Reproductive-system Urinalysis Urine-chemistry

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• ISSN:
  0015-0282
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  383-391
• Volume:
  78
• Issue:
  2
• NIOSHTIC Number:
  nn:20022421
• Citation:
  Fertil Steril 2002 Aug; 78(2):383-391
• Contact Point Address:
  Susan Reutman, 104 Park Avenue, Elsmere, KY 41018
• Email:
  ereutman@hotmail.com
• Federal Fiscal Year:
  2002
• NORA Priority Area:
  Disease and Injury: Fertility and Pregnancy Abnormalities
• Peer Reviewed:
  True
• Source Full Name:
  Fertility and Sterility
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2ce127fbb9ec5f6fb94de645774590539bdaced0b544ba0d9d02b51010e6aaa59e03df6dd8c39dfd6296eaebacc05abeb263faa9a498410966b713738d055e6b
• Download URL:
  https://stacks.cdc.gov/view/cdc/199210/cdc_199210_DS1.pdf
• File Type:
  [PDF - 113.34 KB ]