Determination of Unique Microbial Volatile Organic Compounds Produced by Five Aspergillus Species Commonly Found in Problem Buildings

Details

• Personal Author:
  Chen BT ; Gao, Peng-Fei ; Korley F ; Martin, Jennifer E.
• Description:
  This study identified unique microbial volatile organic compounds (UMVOCs) produced by five Aspergillus species (A. fumigatus, A. versicolor, A. sydowi, A. flavus, and A. niger) cultivated on malt extract agar and gypsum board. The hypothesis was that UMVOCs can be used to predict the presence of Aspergillus species. During the cultivation humidified air was continually supplied and evenly distributed through each of the culture flasks. Volatile metabolites were collected using Tenax TA tubes on Days 8, 16, and 30 after inoculation. The volatile metabolites were determined by gas chromatography/mass spectroscopy after thermal desorption. Nine compounds recognized as UMVOCs--3-methyl-1-butanol; 2-methyl-1-propanol; terpineol; 2-heptanone; 1-octen-3-ol; dimethyl disulfide; 2-hexanone; 3-octanone; and 2-pentylfuran--were found on the cultures in detectable amounts. The first two compounds were detected at the highest frequency when combining both media. The first four compounds were found to be the dominant UMVOCs on gypsum board, which could be used as chemical markers of the common Aspergillus species grown indoors. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution Air Pollution, Indoor Energy Metabolism Environmental Health Fungi Humidity Microbiology Occupational Health Safety
• Keywords:
  Air-contamination Air-quality Author Keywords: Aspergillus Cultures Fungal Contamination Indoor-air-pollution Indoor-environmental-quality Indoor Air Quality Metabolites Microorganisms Odors Organic-chemicals Problem Buildings Unique MVOCs

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• ISSN:
  0002-8894
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  135-140
• Volume:
  63
• Issue:
  2
• NIOSHTIC Number:
  nn:20022402
• Citation:
  Am Ind Hyg Assoc J 2002 Mar/Apr; 63(2):135-140
• Contact Point Address:
  Pengfei Gao, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505
• Email:
  Pgoa@cdc.gov
• Federal Fiscal Year:
  2002
• NORA Priority Area:
  Research Tools and Approaches: Exposure Assessment Methods
• Peer Reviewed:
  True
• Source Full Name:
  American Industrial Hygiene Association Journal
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:b2d65ddbab6912ccd53c4f5130942797eae414ae21bbe9b19937f189a922b0cf616747ddee93329d8dbec25bb36b1bbcf1f3ae6db697fe6e7fb8b3bffc4cef64
• Download URL:
  https://stacks.cdc.gov/view/cdc/199194/cdc_199194_DS1.pdf
• File Type:
  [PDF - 322.43 KB ]