Development of a Filter Assembly to Match the Deposition of Ultrafine Aerosol in the Lung: A Pilot Study with Beryllium

Details

• Personal Author:
  Berakis, Michael ; Hornsby-Myers, Jennifer ; Kent M ; Martin, Stephen B. Jr. ; McCawley M ; Moyer E
• Description:
  A new criterion has previously been proposed for assessing inhalation risk from ultrafine aerosols. This deposited submicrometer particulate (DSP) criterion matches the lung deposition curve for aerosols with a size of <1 um. A method for matching the DSP criterion using racketched polycarbonate filters has been described in the literature, but the sampling results must be adjusted by a correction factor to match the DSP curve. A new design that matches the criterion without the need for any correction factors and has been used with a real-time particle counter to measure processes in the beryllium industry where data suggest that the ultrafine "0.1 microm) fraction of beryllium might be an important metric for predicting disease. [Description provided by NIOSH]
• Subjects:
  Aerosols Beryllium Dust Lung Occupational Health Particulate Matter Respiratory System Safety
• Keywords:
  Author Keywords: Ultrafine Particles Beryllium Beryllium-compounds Diseases Dust-inhalation Dusts Filters Inhalation-studies Lung Deposition Nanotechnology Particulate-dust Particulates Sampling

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• ISSN:
  0003-4878
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  215-218
• Volume:
  46
• NIOSHTIC Number:
  nn:20022268
• Citation:
  Ann Occup Hyg, Inhaled Particles IX, 2002 Dec; 46(Suppl 1):215-218
• Contact Point Address:
  M. McCawley, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
• Editor(s):
  Ogden T; Donaldson K; Cherry N
• Federal Fiscal Year:
  2003
• NORA Priority Area:
  Research Tools and Approaches: Exposure Assessment Methods
• Peer Reviewed:
  True
• Source Full Name:
  Annals of Occupational Hygiene, Inhaled Particles IX
• Supplement:
  1
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:bfeedec9596edb6de5cc2b3f0cdbd4b185b74183eb5f3bbda42ad9224592fda617eff46f7b61cb451a83d51040fce313609841599f0c8012e590680fad0ca361
• Download URL:
  https://stacks.cdc.gov/view/cdc/199100/cdc_199100_DS1.pdf
• File Type:
  [PDF - 105.50 KB ]