Ethnicity and Unprovoked Hypokalemia in the Atherosclerosis Risk in Communities Study

Details

• Personal Author:
  Andrew, Michael E. ; Brown CA ; Jones DW ; Schreiner PJ ; Taylor HA ; Wofford MR ; Wyatt SB ; Young DB
• Description:
  BACKGROUND: Hypertension is more prevalent in the African American population when compared with the European American population in the United States. Unprovoked hypokalemia may lead to hypertension and is associated with several forms of recognized secondary hypertension. METHODS: We investigated the association of ethnicity with unprovoked hypokalemia in the second Atherosclerosis Risk in Communities (ARIC) study examination. Hypokalemia was defined as serum potassium <3.5 mmol/L. RESULTS: A statistically significant association was detected between ethnicity and unprovoked hypokalemia (odds ratio = 5.3; 95% confidence interval = 3.6, 7.7) with unprovoked hypokalemia more prevalent in African Americans both before and after adjustment for important covariates. The unadjusted prevalence for unprovoked hypokalemia was 2.6% for African Americans and 0.5% for European Americans. CONCLUSIONS: We found that the prevalence of unprovoked hypokalemia for African Americans in the ARIC cohort was more than five times that for European Americans. These data suggest that an increased awareness of hypokalemia and its etiology may be indicated for African Americans. [Description provided by NIOSH]
• Subjects:
  Blood Cardiovascular System Diet Ethanol Hematologic Tests Mortality Occupational Health Potassium Compounds Safety
• Keywords:
  ARIC Author Keywords: Hypokalemia Blood-analysis Blood-pressure Cardiovascular-function Dietary-effects Ethanols Ethnicity Hypertension Mortality-rates Potassium Potassium-compounds

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• ISSN:
  0895-7061
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  15
• Issue:
  7
• NIOSHTIC Number:
  nn:20022191
• Citation:
  Am J Hyper 2002 Jul; 15(7) :594-549
• Contact Point Address:
  Health Effects Laboratory Division, National Institute for Occupational Safety and Health, CDC, 1095 Willowdale Road, M.S. 4020, Morgantown, WV 26505
• Email:
  mandrew@cdc.gov
• Federal Fiscal Year:
  2002
• NORA Priority Area:
  Other Occupational Concerns ; Cardiovascular Disease
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Hypertension
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6a050c2ba084969da7cadda7d943d99ab99f5c43b7e0307d9f880d77be4b90fc334d5d0177844d5f590931bb8811ed0bb69e750bd3290493fa37be8bc061ee8a
• Download URL:
  https://stacks.cdc.gov/view/cdc/199059/cdc_199059_DS1.pdf
• File Type:
  [PDF - 92.95 KB ]