Epidemiology of Occupational Cancer

Details

• Personal Author:
  Bang KM
• Description:
  The incidences, causes and characteristics of occupational cancer were reviewed. A discussion of the magnitude of cancers attributable to occupation was provided. Characteristics of occupational cancers included varying latency periods, histological types, and demographic variables, as well as definite dose response relationships. The existence of threshold values for safe levels of carcinogen exposure was considered controversial. Carcinogens were classified according to the degree of evidence indicating carcinogenicity: sufficient, limited, insufficient, and lack of evidence. The known lung, skin, and liver carcinogens were listed. The main goal in epidemiological studies of occupational cancer was regarded as the study of cancer morbidity and mortality in working groups. Epidemiological evidence was reviewed which related various carcinogens to the diseases they cause, including asbestos (1332214) to lung cancer, mesothelioma and asbestosis; aromatic amines to bladder cancer; alkylating agents to lung cancer and leukemia; benzene (71432) to myelogenous leukemia; polycyclic aromatic hydrocarbons to scrotal and lung cancer; vinyl-chloride (75014) to angiosarcoma; metals to lung and skin cancer; and metalworking fluids to stomach, bladder, pancreas, larynx, and skin cancers. Mortality data, cancer survey data, and cancer registries were considered useful approaches to surveillance. Types of occupational cancer surveillance included disease based surveillance, exposure based surveillance, and medical screening. The five working populations recommended for further occupational cancer research were listed as asbestos workers, motor vehicle operators, machinists and related workers, electric workers, and metal workers. The author concludes that cancer prevention and control should incorporate primary prevention strategies that focus on exposure avoidance, secondary prevention strategies that focus on medical screening, and suitable surveillance programs. [Description provided by NIOSH]
• Subjects:
  Epidemiology Liver Lung Lung Diseases Mortality Neoplasms Occupational Diseases Occupational Health Respiratory System Respiratory Tract Diseases Safety Skin Skin Diseases Urogenital Diseases Urogenital System

  More +
• Keywords:
  Bladder-cancer Cancer-rates Humans Liver-cancer Lung-cancer Lymphatic-cancer Mortality-data NIOSH-Author Occupational-diseases Skin-cancer
• ISBN:
  9781560532262
• ISSN:
  0885-114X
• Publisher:
  Hanley and Belfus, Inc.
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  467-485
• Volume:
  11
• Issue:
  3
• NIOSHTIC Number:
  nn:00235990
• Citation:
  Occup Med: State of the Art Rev 1996 Jul; 11(3):467-485
• CAS Registry Number:
  Asbestos (CAS RN 1332-21-4) ; Benzene (CAS RN 71-43-2) ; Vinyl chloride (CAS RN 75-01-4)
• Editor(s):
  Bang KM
• Federal Fiscal Year:
  1996
• Peer Reviewed:
  True
• Source Full Name:
  Occupational Medicine: State of the Art Reviews. Occupational Epidemiology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:66b29cea85ebf7999ffa420f10328a658d00c9e49b1137e90686a5104d183a2d839b8b494da453b8c6317a60324db1d386b29b84926946b6a3a32e8765e8eba1
• Download URL:
  https://stacks.cdc.gov/view/cdc/197808/cdc_197808_DS1.pdf
• File Type:
  [PDF - 1.07 MB ]