1-Hydroxypyrene Levels in Coal-Handling Workers at a Coke Oven

Details

• Personal Author:
  Kiefer, Max ; Malkin, Robert ; Tolos, William P.
• Description:
  An investigation was undertaken to assess the dermal pyrene (129000) exposure risk faced by coke oven workers. Twenty two workers from the coal-tar sludge handling area of a coke oven were enrolled in this study. Each subject provided a urine sample and completed a questionnaire on work practices, diet, and smoking habit. Urine samples were collected before and after subjects' work shifts, and were analyzed to determine levels of 1-hydroxypyrene (5315797) (1- HP), a pyrene metabolite. During work shifts personal breathing zone samples and bulk samples were collected and analyzed for polycyclic aromatic hydrocarbons and coal tar pitch volatiles. The mean preshift and postshift 1-HP levels were 1.00 and 1.7 micromoles/moles creatine, respectively. Levels of pyrene detected in bulk and breathing zone samples were found to be minimal. The authors conclude that coke oven workers are at risk for dermal exposure to pyrene. [Description provided by NIOSH]
• Subjects:
  Energy Metabolism Hydrocarbons Occupational Exposure Occupational Health Polycyclic Aromatic Hydrocarbons Pyrenes Safety Skin Urine
• Keywords:
  Coke-oven-workers Coke-ovens Humans Metabolites NIOSH-Author Occupational-exposure Polycyclic-aromatic-hydrocarbons Skin-exposure Urinalysis
• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; DBBS - Division of Biomedical and Behavioral Sciences
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  38
• Issue:
  11
• NIOSHTIC Number:
  nn:00235229
• Citation:
  J Occup Environ Med 1996 Nov; 38(11):1141-1144
• Contact Point Address:
  Robert Malkin, DrPH, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Mail Stop R-10, Cincinnati, OH 45226
• CAS Registry Number:
  1-Hydroxypyrene (CAS RN 5315-79-7) ; Pyrene (CAS RN 129-00-0)
• Federal Fiscal Year:
  1997
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:10e2d8f8c47a86addc1662f00c13f69c67939d00fca297ebdf8604375177fe71fd9e3424be924841e1ecd92cc4f4fcdc907388f0e8c92d3763096363b30c224f
• Download URL:
  https://stacks.cdc.gov/view/cdc/197765/cdc_197765_DS1.pdf
• File Type:
  [PDF - 195.43 KB ]