Exposure to Diesel Exhaust and Risk of Lung Cancer in the Trucking Industry

Details

• Personal Author:
  Bailey CR ; LeMasters GK ; Smith RJ ; Stayner, Leslie T. ; Steenland NK ; Yiin JH
• Description:
  A quantitative exposure-response analysis of diesel exhaust and lung cancer among workers in the trucking industry was conducted with a new exposure model developed by the Environmental Protection Agency (EPA). To estimate past exposures, EPA generated 2,500 diesel particulate matters (DPM) for each calendar year from 1950 to 1990 and for each of the four exposed job categories plus the nonexposed. Logistic regression relating lung cancer risk and cumulative diesel particulate matters and adjusting for smoking status, age at death, and reported asbestos exposure was used. The means of the 2,500 annual job-specific DPM were used for exposure estimates in the exposure-response analyses. As a sensitivity analysis, Monte Carlo simulations using the full distributions of these DPM were conducted. Using the new exposure model, the estimated cumulative exposures to diesel exhaust for all job categories were significatnly lower than those previously estimated by Steenland et al. The estimated excess risks, however, were similar. For a male truck driver exposed to 5 microg/m3 of diesel particulate mass, the estimated lifetime excess risk of lung cancer in the current analysis was 1.9% compared to 1.6% in the previous study. [Description provided by NIOSH]
• Subjects:
  Aerosols Carcinogens Dust Environmental Monitoring Epidemiology Lung Lung Diseases Neoplasms Occupational Health Particulate Matter Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Transportation Vehicle Emissions

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• Keywords:
  Aerosol-particles Diesel-emissions Diesel-exhausts Dusts Exhaust-gases Exposure-assessment Lung-cancer Particulate-dust Particulates Pulmonary-system-disorders Quantitative-analysis Respiratory-system-disorders Risk-analysis Risk-factors Statistical-analysis Transportation-industry Transportation-workers Truck-drivers Trucking

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• Publisher:
  Society for Risk Analysis
• Document Type:
  Text
• Genre:
  Abstract or Summary ; Proceedings
• Place as Subject:
  Maryland ; Ohio ; OSHA Region 3 ; OSHA Region 5 ; Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  EID - Education and Information Division ; DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:20027208
• Citation:
  Society for Risk Analysis 2003 Annual Meeting. Bridging Risk Divides, Baltimore, Maryland, December 7-10, 2002. McLean, VA: Society for Risk Analysis, 2003 Dec; :120
• Email:
  jcy5@cdc.gov
• Federal Fiscal Year:
  2004
• Peer Reviewed:
  False
• Source Full Name:
  Society for Risk Analysis 2003 Annual Meeting Bridging Risk Divides, Baltimore, Maryland, December 7-10, 2002
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:983dc401df4c056b01f199c1e5c9024ad8d44dd8defa3707d68e6f453dfdba3d3809e14470736a6e3af4eb6216c80af7200ac237190c21c564902fe5427c397f
• Download URL:
  https://stacks.cdc.gov/view/cdc/197506/cdc_197506_DS1.pdf
• File Type:
  [PDF - 410.84 KB ]