Differences in Mortality by Radiation Monitoring Status in an Expanded Cohort of Portsmouth Naval Shipyard Workers

Details

• Personal Author:
  Chen P-H ; Couch, James R. ; Daniels, Robert D. ; Kinnes, Gregory M. ; Kubale, Travis L. ; Schubauer-Berigan, Mary K. ; Silver, Sharon R. ; Taulbee TD ; Yiin JH ; Zaebst, Dennis D. ; Chen P-H ; Couch, James R. ; Daniels, Robert D. ; Kinnes, Gregory M. ; Kubale, Travis L. ; Schubauer-Berigan, Mary K. ; Silver, Sharon R. ; Taulbee TD ; Yiin JH ; Zaebst, Dennis D.
• Description:
  Studies of leukemia and lung cancer mortality at the Portsmouth Naval Shipyard (PNS) have yielded conflicting results. In an expanded cohort of PNS workers employed between 1952 and 1992 and followed through 1996, the all-cause standardized mortality ratio (SMR) was 0.95 (95% confidence interval, 0.93-0.96). Employment duration SMRs were elevated with confidence intervals excluding 1.00 for lung cancer, esophageal cancer, and all cancers combined. Leukemia mortality was as expected overall, but standardized rate ratio analyses showed a significant positive linear trend with increasing external radiation dose. The role of solvent exposures could not be evaluated. Findings differed by radiation monitoring subcohort, with excess asbestosis deaths limited to radiation workers and several smoking-related causes of death higher among nonmonitored workers. At PNS, asbestos exposure and possibly smoking could be nonrandomly distributed with respect to radiation exposure, suggesting potential for confounding in internal analyses of an occupational cohort. [Description provided by NIOSH]
• Subjects:
  Epidemiology Hematologic Diseases Lung Lung Diseases Mortality Neoplasms Occupational Health Radiation Respiratory System Respiratory Tract Diseases Safety Ships Smoke Smokers Solvents Tobacco Products

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• Keywords:
  Blood-disorders Cigarette-smoking Lung-cancer Mortality-data Mortality-rates Mortality-surveys Pulmonary-cancer Pulmonary-system-disorders Radiation-exposure Radiation-hazards Respiratory-system-disorders Shipbuilding-industry Shipyard-industry Shipyard-workers Shipyards Statistical-analysis Tobacco-smoke

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• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  Maine ; Ohio ; OSHA Region 1 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Volume:
  46
• Issue:
  7
• NIOSHTIC Number:
  nn:20025691
• Citation:
  J Occup Environ Med 2004 Jul; 46(7):677-690
• Contact Point Address:
  Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226
• Email:
  zre4@cdc.gov
• CAS Registry Number:
  Asbestos (CAS RN 1332-21-4) ; Asbestos (CAS RN 1332-21-4)
• Federal Fiscal Year:
  2004
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:bac9c606640636012b7af78b725e0d096dde116f484051961f5f1e9c2c4cafce0eac4aea7a36416c3448f9fa306d90a41d27401e6434760aff1c4fcc10d456c5
• Download URL:
  https://stacks.cdc.gov/view/cdc/196956/cdc_196956_DS1.pdf
• File Type:
  [PDF - 305.55 KB ]