Mortality Patterns Among Workers Exposed to Styrene in the Reinforced Plastic Boatbuilding Industry: An Update

Details

• Personal Author:
  Davis-King K ; Dong M ; Okun, Andrea H. ; Ruder, Avima M. ; Ward, Elizabeth M.
• Description:
  BACKGROUND: Mortality was updated through 1998 for 5,204 workers exposed to styrene between 1959 and 1978 at two reinforced plastic boatbuilding plants. The a priori hypothesis: leukemia and lymphoma excesses would be found. METHODS: Standardized mortality ratios (SMR) and 95% confidence intervals (CI) used Washington State and U.S. rates. RESULTS: Overall, 860 deaths occurred (SMR 1.09, CI 1.02-1.17), with excess mortality for esophageal cancer (n = 12, SMR 2.30, CI 1.19-4.02), prostate cancer (n = 24, SMR 1.71, CI 1.09-2.54), and accidents (n = 99, SMR 1.26, CI 1.02-1.53). Among 2,062 highly exposed workers, urinary tract cancer (n = 6, SMR 3.44, CI 1.26-7.50) and respiratory disease (n = 12, SMR 2.54, CI 1.31-4.44) rates were elevated. Urinary tract cancer SMR increased with duration of employment. CONCLUSIONS: We found no excess leukemia or lymphoma mortality. Unanticipated excess urinary tract cancer and respiratory disease mortality, possibly associated with styrene exposure, are difficult to interpret and could be chance findings. [Description provided by NIOSH]
• Subjects:
  Epidemiology Hematologic Diseases Mortality Neoplasms Occupational Health Polystyrenes Respiratory Tract Diseases Safety Ships Styrene Urogenital Diseases Urogenital System

  More +
• Keywords:
  Author Keywords: Styrene Blood-disorders Boat-manufacturing-industry Cancer Cancer-rates Cancer Mortality Cohort Mortality Study Leukemia Mortality-data Mortality-rates Mortality-surveys Pulmonary-system-disorders Reinforced Plastic Industry Respiratory-system-disorders Statistical-analysis Styrene-resins Styrenes Urinary Tract Cancer Urogenital-system-disorders

  More +
• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  165-176
• Volume:
  45
• Issue:
  2
• NIOSHTIC Number:
  nn:20025688
• Citation:
  Am J Ind Med 2004 Feb; 45(2):165-176
• Contact Point Address:
  National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226
• Email:
  amr2@cdc.gov
• CAS Registry Number:
  Styrene (CAS RN 100-42-5)
• Federal Fiscal Year:
  2004
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8ac6dd5d7c595473770f6f90e00e840c696ab8faac608855ec71af1658409ad574af3326400f3b02baed5bb42ca977704a0bd8e2a2de44d38eafa195ef052bfc
• Download URL:
  https://stacks.cdc.gov/view/cdc/196953/cdc_196953_DS1.pdf
• File Type:
  [PDF - 142.71 KB ]