Symptom Onset in the First 2 Years of Employment at a Wood Products Plant Using Diisocyanates: Some Observations Relevant to Occupational Medical Screening

Details

• Personal Author:
  Petsonk, Edward L. ; Wang, Mei Lin
• Description:
  Questionnaires are essential tools for medical screening, but their role in monitoring workers at increased risk of occupational asthma (OA) remains indeterminate. Employees who were at a newly established wood products plant without previous exposure to methylene diphenyl diisocyanate (MDI) completed an initial questionnaire and from one to four follow-up questionnaires during a 2-year period. Onset of symptoms in 132 workers was assessed by exposure groups and modeled using generalized estimating equations. Onset of attacks of dyspnea with wheeze, attacks of dyspnea or cough at rest, and chest tightness were significantly associated with MDI exposure after controlling for age, smoking, and wood dust exposure. Onset of cough on most days was significantly related to smoking and dust. Onset of phlegm production was significantly related to both MDI and dust exposure. Onset of certain symptoms is significantly associated with MDI exposure. Early detection of MDI-associated health effects using a short screening questionnaire appears feasible. [Description provided by NIOSH]
• Subjects:
  Asthma Asthma, Occupational Dust Environmental Monitoring Occupational Diseases Occupational Exposure Occupational Health Respiratory System Risk Assessment Risk Factors Safety Smokers Surveys And Questionnaires Wood Workplace

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• Keywords:
  Asthma Author Keywords: Occupational Asthma Bronchial-asthma Diisocyanate Exposure-assessment Exposure-levels Medical-screening Medical Screening Monitoring-systems Occupational-diseases Occupational-exposure Occupational-health Occupational Health Services Questionnaires Respiratory Risk-analysis Risk-factors Signs And Symptoms Smoking Surveillance Symptom Onset Wood-dusts Wood-products Work-environment Workers

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• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  226-233
• Volume:
  46
• Issue:
  3
• NIOSHTIC Number:
  nn:20025448
• Citation:
  Am J Ind Med 2004 Sep; 46(3):226-233
• Contact Point Address:
  Dr. Mei-Lin Wang, NIOSH, Mail Stop H-G900.2, 1095 Willowdale Road, Morgantown, WV 26505
• Email:
  mlw4@cdc.gov
• CAS Registry Number:
  Diphenylmethane diisocyanate (CAS RN 101-68-8)
• Federal Fiscal Year:
  2004
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d1e416d8db66a9f74830340949703d19dbb738acdb117d95bcbdbb3abbab7606a7ebc1319f558d4e83493e1f4b286b1419f50c5fda2ac19ad2af2cd256d39255
• Download URL:
  https://stacks.cdc.gov/view/cdc/196808/cdc_196808_DS1.pdf
• File Type:
  [PDF - 111.69 KB ]