Comparison of a Convective Mixing Model’s Predictions to Empirical Results for Aerosol Dispersion in the Human Lung

Details

• Personal Author:
  Christie I ; Ganser, Jean Cox ; McCawley MA
• Description:
  Recent modeling work has attempted to use axial diffusion to explain the observed dispersion of an aerosol bolus in transit through the lung (Edwards, 1994). This type of modeling attempts to derive from first principles the underlying mechanism of aerosol dispersion. An alternative approach has used mixing theory derived from reactor vessels to surmount problems encountered in small-scale mixing (McCawley et al., 1988). Noting that Oltman (1985) had used an approach that is mathematically similar in applying network theory to this problem, it was decided to try to relate the number of vessels in series to the number of bifurcated generations in the lung. [Description provided by NIOSH]
• Subjects:
  Aerosols Lung Occupational Health Respiratory System Safety
• Keywords:
  Aerosol-dispensers Aerosol-particles Aerosol-sampling Lung-function Models
• ISBN:
  0080427405
• ISSN:
  0003-4878
• Publisher:
  Pergamon
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  41
• NIOSHTIC Number:
  nn:20025019
• Citation:
  Ann Occup Hyg, Inhaled Particles VIII 1997 Jan; 41(Suppl 1):571-575
• Editor(s):
  Cherry N; Ogden T
• Federal Fiscal Year:
  1997
• Peer Reviewed:
  True
• Source Full Name:
  Annals of Occupational Hygiene, Inhaled Particles VIII
• Supplement:
  1
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d3cb30198b14efb449d4d7718d39efd190b3601fa6b5a207962f1e066fde4ab8cc6c6c54465c51d1adee7fa15cce7568fd020a78f21e5c0881943673592d094c
• Download URL:
  https://stacks.cdc.gov/view/cdc/196539/cdc_196539_DS1.pdf
• File Type:
  [PDF - 343.31 KB ]