Methods for assessing risks of dermal exposures in the workplace

Details

• Personal Author:
  Boeniger, Mark F. ; McDougal JN
• Description:
  The skin as a route of entry for toxic chemicals has caused increasing concern over the last decade. The assessment of systemic hazards from dermal exposures has evolved over time, often limited by the amount of experimental data available. The result is that there are many methods being used to assess safety of chemicals in the workplace. The process of assessing hazards of skin contact includes estimating the amount of substance that may end up on the skin and estimating the amount that might reach internal organs. Most times, toxicology studies by the dermal route are not available and extrapolations from other exposure routes are necessary. The hazards of particular chemicals can be expressed as "skin notations", actual exposure levels, or safe exposure times. Characterizing the risk of a specific procedure in the workplace involves determining the ratio of exposure standards to an expected exposure. The purpose of this review is to address each of the steps in the process and describe the assumptions that are part of the process. Methods are compared by describing their strengths and weaknesses. Recommendations for research in this area are also included. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Occupational Health Risk Assessment Safety Skin Skin Absorption Workplace
• Keywords:
  Exposure-assessment Risk-analysis Skin-absorption Workplace-studies
• ISSN:
  1040-8444
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  291-327
• Volume:
  32
• Issue:
  4
• NIOSHTIC Number:
  nn:20043573
• Citation:
  Crit Rev Toxicol 2002 Jul-Aug; 32(4):291-327
• Federal Fiscal Year:
  2002
• Peer Reviewed:
  True
• Source Full Name:
  Critical Reviews in Toxicology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:5c83df30d1687a6aacdd2deb49f8e2e740557d7129301c8e46a7c9f5f01c8f950058c9c14b796654ab7fce5e1ed274d557c977dab4ba5b77e80db9695e4e9409
• Download URL:
  https://stacks.cdc.gov/view/cdc/195442/cdc_195442_DS1.pdf
• File Type:
  [PDF - 754.71 KB ]