Serum bisphenol-A concentration and sex hormone levels in men

Details

• Personal Author:
  Bai L ; Ding L ; Gao E ; Li D-K ; Li G ; Miao M ; Ran M ; Wang J ; Wu T ; Yuan W ; Zhou Q
• Description:
  OBJECTIVE: To evaluate the association between serum bisphenol-A (BPA) concentration and sex hormone levels in men. DESIGN: Cross-sectional study. SETTING: Not applicable. PATIENT(S): A total of 290 men with or without BPA exposure in the workplace. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Serum sex hormone levels. RESULT(S): After adjustment for potential confounders using linear regression, increasing serum BPA concentration was statistically significantly associated with [1] decreased androstenedione levels, [2] decreased free testosterone levels, [3] decreased free androgen index, and [4] increased sex hormone-binding globulin levels. Comparison of hormone levels between workers exposed and unexposed to BPA showed similar associations. CONCLUSION(S): Exposure to a high BPA level may impact sex hormone levels in men. [Description provided by NIOSH]
• Subjects:
  Aging Biphenyl Compounds Blood Endocrine System Hematologic Tests Men Occupational Health Safety Sex Characteristics
• Keywords:
  Age-groups Author Keywords: Bisphenol-A Biphenyls Blood-analysis Blood-cells BPAl Endocrine Disruption Exposure-levels Hormones Humans Sex-factors Sex Hormones

  More +
• ISSN:
  0015-0282
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  478-482
• Volume:
  100
• Issue:
  2
• NIOSHTIC Number:
  nn:20043531
• Citation:
  Fertil Steril 2013 Aug; 100(2):478-482
• Contact Point Address:
  Jintao Wang, M.D., Ph.D., Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan, People's Republic of China
• Email:
  wangjt59@163.com
• Federal Fiscal Year:
  2013
• Performing Organization:
  Kaiser Foundation Research Institute
• Peer Reviewed:
  True
• Start Date:
  20030930
• Source Full Name:
  Fertility and Sterility
• End Date:
  20110929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c3e6425b2010c6eca07a58ffabdff9761d4c547229e195b976689586e4df07b6ed143cac0f10ae6633517e25eae50fb5a646ac61f25a3bb39d25014527e1f294
• Download URL:
  https://stacks.cdc.gov/view/cdc/195410/cdc_195410_DS1.pdf
• File Type:
  [PDF - 148.06 KB ]