The association between obstructive sleep apnea and hypertension by race/ethnicity in a nationally representative sample

Details

• Personal Author:
  Grandner M ; Gurubhagavatula I ; Jackson N ; Keenan BT ; Sands-Lincoln M ; Whinnery J
• Description:
  The association between obstructive sleep apnea (OSA) and hypertension by race/ethnicity has not been well characterized in a national sample. Adult participants in the 2007-2008 National Health and Nutrition Examination Survey were reviewed by self-report of sleep apnea diagnosis, snorting, gasping or stopping breathing during sleep, and snoring to derive whether OSA was probable (pOSA). Multivariable logistic regression determined whether pOSA predicted hypertension in the overall cohort, and by body mass index (BMI) group and ethno-racial strata. pOSA predicted hypertension in several groups: (1) Within BMI strata, there was a significant association among overweight individuals [odds ratio [OR], 1.82; 95% confidence interval [CI], 1.26-2.62); (2) In race/ethnicity subgroups, the association was significant among Hispanic/Latinos (OR, 1.69; 95% CI, 1.13-2.53) and whites (OR, 1.40; 95% CI, 1.07-1.84); (3) In models stratified by both race/ethnicity and BMI, pOSA predicted hypertension among overweight black/African Americans (OR, 4.74; 95% CI, 1.86-12.03), overweight whites (OR, 1.65; 95% CI, 1.06-2.57), and obese Hispanic/Latino participants (OR, 2.01; 95% CI, 1.16-3.49). A simple, self-report tool for OSA was strongly associated with hypertension, and may serve as a potential future opportunity for OSA diagnosis. [Description provided by NIOSH]
• Subjects:
  Body Weight Cardiovascular Diseases Cardiovascular System Occupational Health Safety
• Keywords:
  Body Weight Hypertension Sleep Apnea Sociological Factors Weight Factors
• ISSN:
  0748-450X
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  15
• Issue:
  8
• NIOSHTIC Number:
  nn:20043372
• Citation:
  J Clin Hypertens 2013 Aug; 15(8):593-599
• Contact Point Address:
  Megan Sands-Lincoln, PhD, MPH, Center for Sleep and Circadian Neurobiology, Perelman School of Medicine, University of Pennsylvania, 3624 Market Street, Suite 205, Philadelphia, PA 19104
• Email:
  megsands@mail.med.upenn.edu
• Federal Fiscal Year:
  2013
• Performing Organization:
  University of Pennsylvania
• Peer Reviewed:
  True
• Start Date:
  20070801
• Source Full Name:
  Journal of Clinical Hypertension
• End Date:
  20130701
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e7371f5380444125e43fd796791a106a94ea1cf1f3ba5ab920196b63cadf25f2f548cf38a4f23cf9ed1f27c2c800711fc789eeb1e235e6976356a96a59ded3a4
• Download URL:
  https://stacks.cdc.gov/view/cdc/195289/cdc_195289_DS1.pdf
• File Type:
  [PDF - 135.62 KB ]