Cluster of work-related asthma reveals a new asthmagen: AMT at ChemDesign

Details

• Personal Author:
  Pechter E
• Description:
  In this issue we present a cluster investigation prompted by a report to SENSOR that identified a new sensitizing agent. An astute pulmonologist identified a case of work-related asthma that he suspected was related to other cases being seen by his colleagues. A note written on the Confidential Report of Occupational Disease and Injury alerted OHSP to the cluster. OHSP received Technical Assistance from NIOSH, which performed a comprehensive evaluation including medical, industrial hygiene and toxicological assessments necessary to identify a new asthma-causing agent. Sentinel surveillance succeeded in several important public health functions. Initially, a cluster of WRA was revealed. Subsequent investigation of this cluster provided important information about a previously unrecognized asthmagen, AMT (amino mercapto triazole). The manufacturer implemented methods to reduce exposures to this hazardous chemical. Additionally, state and federal occupational health agencies collaborated to enhance communication and provide a comprehensive evaluation in response to knowledgeable medical evaluation. This sentinel surveillance system relies upon health care providers. Accurate diagnosis of asthma, with follow-up that links symptoms to work are the cornerstones of prevention. Please continue to report confirmed and suspected work-related asthma cases to OHSP. [Description provided by NIOSH]
• Subjects:
  Amino Acids Asthma Asthma, Occupational Environmental Monitoring Hazardous Substances Lung Lung Diseases Manufacturing And Industrial Facilities Occupational Diseases Occupational Exposure Occupational Health Respiratory System Respiratory Tract Diseases Safety Toxicology Workplace

  More +
• Keywords:
  Amino-compounds Amino-groups Bronchial-asthma Chemical-industry-workers Chemical-manufacturing-industry Employee-exposure Exposure-assessment Hazardous-materials Health-care Industrial-hygiene Lung-disease Lung-irritants Medical-screening Occupational-diseases Occupational-exposure Occupational-health Occupational-respiratory-disease Pulmonary-system-disorders Respiratory-system-disorders Surveillance-programs Work-environment

  More +
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-2
• NIOSHTIC Number:
  nn:20042697
• Citation:
  SENSOR Occup Lung Dis Bull 2002 Sep; :1-2
• Contact Point Address:
  Massachusetts Department of Public Health, Occupational Health Surveillance Program, 250 Washington Street, 6th Floor, Boston, MA 02108
• CAS Registry Number:
  3-amino-5-mercapto-1,2,4-triazole (CAS RN 16691-43-3)
• Federal Fiscal Year:
  2002
• Performing Organization:
  Massachusetts State Department of Public Health
• Peer Reviewed:
  False
• Start Date:
  19880415
• Source Full Name:
  SENSOR Occupational Lung Disease Bulletin
• End Date:
  20050929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:77e173905e47706ca67a070085f83d7c868138a0cadc93759e24a084251e2cd1f2f72bc7c277605462a31ccb478fcc92704ed85bd2cc02e1d8d89e802ae05c42
• Download URL:
  https://stacks.cdc.gov/view/cdc/194836/cdc_194836_DS1.pdf
• File Type:
  [PDF - 115.57 KB ]