Leukemia among male construction workers in California, 1988-2007

Details

• Personal Author:
  Calvert, Geoffrey M. ; Cress R ; Deapen D ; Luckhaupt SE ; Schumacher P ; Shen R
• Description:
  A total of 18,708 male cases of leukemia from the California Cancer Registry, including 1,703 cases usually employed in construction, were each matched with up to five controls from the same source who were diagnosed with cancers not thought to be related to exposures common in construction. Compared to other workers, construction workers were found to have a significantly elevated risk for all leukemia combined (morbidity odds ratio [MOR] = 1.14, 95% confidence interval [CI] = 1.08, 1.20), acute lymphocytic leukemia (ALL) (MOR = 1.30, 95% CI = 1.07, 1.58), acute myeloid leukemia (AML) (MOR = 1.15, 95% CI = 1.03, 1.27) and chronic myeloid leukemia (CML) (MOR = 1.25, 95% CI = 1.09, 1.44). Among the different construction occupations, the highest MOR for all leukemia was among carpet installers (MOR = 1.99, 95% CI = 1.16, 3.44), followed by plumbers (MOR = 1.28, 95% CI = 1.03, 1.59) and laborers (MOR = 1.26, 95% CI = 1.12, 1.42). Other associations were limited to specific construction occupations, leukemia subtypes and/or racial/ethnic groups. These associations should be further studied with more in-depth exposure assessment. [Description provided by NIOSH]
• Subjects:
  Blood Construction Industry Epidemiology Men Morbidity Neoplasms Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety

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• Keywords:
  Author Keywords: Cancer Cancer Cancer-rates Construction Construction-industry Construction-workers Employee-exposure Employee-health Floor Coverings Floors Leukemia Leukemogenesis Lymphatic-cancer Morbidity-rates Myeloid-tissue Occupational Plumbers Risk-factors Statistical-analysis Surveillance Surveillance-programs

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• ISSN:
  1042-8194
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  53
• Issue:
  11
• NIOSHTIC Number:
  nn:20041696
• Citation:
  Leuk Lymphoma 2012 Nov; 53(11):2228-2236
• Contact Point Address:
  Sara E. Luckhaupt, MD, MPH, NIOSH, DSHEFS, 4676 Columbia Parkway, MS R-17, Cincinnati, OH 45226, USA
• Email:
  sluckhaupt@cdc.gov
• Federal Fiscal Year:
  2013
• NORA Priority Area:
  Construction
• Peer Reviewed:
  True
• Source Full Name:
  Leukemia & Lymphoma
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d136a683932ff02d38314ee7c4a962d8ecde0d2643a16be8e0f2518e1904972417fd4b0d8c71f15e929d490f39316901a24441f084f80761bece80f8475bac00
• Download URL:
  https://stacks.cdc.gov/view/cdc/194187/cdc_194187_DS1.pdf
• File Type:
  [PDF - 383.92 KB ]