Occupational exposure to o-tolidine

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  "A method is described for the sampling and analysis of o-tolidine (119937) , based on a method successfully used for benzidine (92875). Air is drawn through a two stage sampler consisting of a high efficiency fiber filter and a silica gel bed which collects o- tolidine and its salts. The filter and sorbent sections of the sampler are transferred to stoppered tubes and the o-tolidine is desorbed. A triethylamine/methyl-alcohol solution is injected into a high pressure liquid chromatograph. Peak readings are obtained and compared with a standard calibration curve. This method can detect 0.15 to 6.5 micrograms of benzidine per sample (3 to 130 micrograms per cubic meter for a 50 liter air sample) using 0.5 milliliters of desorbing solution and a 10 microliter injection into the liquid chromatograph. The authors suggest that the range of detection for o-tolidine should be similar to that for benzidine. The limit of detection for o-tolidine is predicted to be about 0.05 micrograms per sample." - NIOSHTIC-2
• Subjects:
  Occupational Health Safety
• Series:
  NIOSH Numbered Publications
• Subseries:
  Criteria Document
• DOI:
  https://doi.org/10.26616/NIOSHPUB78179
• Document Type:
  Text
• Genre:
  Standards
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  viii, 77 numbered pages
• NIOSHTIC Number:
  nn:00094156
• Collection(s):
  Guidelines and Recommendations National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2acd43900dcf26d8a6730ed2535622e72a23218f3e7ef282ac592b3e921f4edcb580b72423648bff2556306a8d3640482e5d18285f1239995f65f87beed2b8b8
• Download URL:
  https://stacks.cdc.gov/view/cdc/19418/cdc_19418_DS1.pdf
• File Type:
  [PDF - 1.83 MB ]