Evaluation of silicosis in response to highest task silica exposure with imputed values where no measurements were made

Details

• Personal Author:
  Ayer, Howard E. ; Clark S ; Grimsley F ; Rice C ; Rinsky, Robert C. ; Succop P
• Description:
  More than one million workers are exposed annually to silica in the workplace. The purpose and specific aims of this study were to investigate ways to estimate silica exposure in unsampled tasks and to evaluate the relationship between highest task silica exposure imputed and the development of silicosis. Data from the North Carolina Dusty Trades, a unique resource for exposure-response studies of the effects of silica exposure, is the basis for the study. Three methods of imputation were used. The methods were estimating exposures based on the mean exposure at sampled commodity-specific tasks, the lower bound of the 95% confidence interval of the median of commodity-specific tasks, and maximum likelihood estimate. The three imputation methods are described and presented. The results of this study indicate that the highest task-related silica exposure is related to the development of silicosis with an odds ratio of 2.22 and is statistically significant (p=0.001). These results can serve as a guide to changes in sampling methods and targeted control techniques that should be implemented to decrease disease in the workplace. [Description provided by NIOSH]
• Subjects:
  Dust Environmental Exposure Environmental Monitoring Epidemiology Lung Diseases Occupational Exposure Occupational Health Respiratory Tract Diseases Safety Silicon Compounds Silicon Dioxide

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• Keywords:
  Analytical-methods Analytical-processes Dose-response Dust-control Dust-exposure Dust-sampling Employee-exposure Exposure-assessment Industrial-exposures Information-retrieval-systems Lung-disorders Occupational-exposure Pulmonary-system-disorders Respiratory-system-disorders Sampling-methods Silica-dusts Silicon-compounds Silicosis Task-performance

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• Publisher:
  American Industrial Hygiene Association
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary
• Place as Subject:
  Florida ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  80
• NIOSHTIC Number:
  nn:20041649
• Citation:
  American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida. Fairfax, VA: American Industrial Hygiene Association, 2000 May; :80
• CAS Registry Number:
  Quartz (SiO2) (CAS RN 14808-60-7) ; Silica (CAS RN 7631-86-9)
• Federal Fiscal Year:
  2000
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  False
• Start Date:
  19980930
• Source Full Name:
  American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida
• End Date:
  20010331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:29759ad3510afd50aa135c97e53639ef4b0ab683adb90e9170752694b8e280fe0e82a7a8380f5b6b6df35532c4eb505bce698fd2f644c4f9e348d535666a6c10
• Download URL:
  https://stacks.cdc.gov/view/cdc/194149/cdc_194149_DS1.pdf
• File Type:
  [PDF - 1.03 MB ]