Psychosocial job stress and immunity: a systematic review

Details

• Personal Author:
  Nakata A
• Description:
  The purpose of this review was to provide current knowledge about the possible association between psychosocial job stress and immune parameters in blood, saliva, and urine. Using bibliographic databases (PubMed, PsychINFO, Web of Science, Medline) and the snowball method, 56 studies were found. In general, exposure to psychosocial job stress (high job demands, low job control, high job strain, job dissatisfaction, high effort-reward imbalance, overcommitment, burnout, unemployment, organizational downsizing, economic recession) had a measurable impact on immune parameters (reduced NK cell activity, NK and T cell subsets, CD4+/CD8+ ratio, and increased inflammatory markers). The evidence supports that psychosocial job stresses are related to disrupted immune responses but further research is needed to demonstrate cause-effect relationships. [Description provided by NIOSH]
• Subjects:
  Blood Hematologic Tests Immune System Mental Health Occupational Health Safety Stress, Psychological Urine Workplace
• Keywords:
  Author Keywords: Psychosocial Job Stress Biological-systems Blood-tests Cell-function Cellular-reactions Immune-reaction Immune-system Immune System Job-stress Psychological-factors Psychoneuroimmunology Salivary-glands Sociological-factors Systematic Review Urinalysis Work-environment Work-operations Work-organization Work-performance Work Environment Worker-health Worker-motivation Workers

  More +
• ISBN:
  9781627030700
• ISSN:
  1064-3745
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  39-75
• Volume:
  934
• NIOSHTIC Number:
  nn:20041482
• Citation:
  Methods Mol Biol 2012 Aug; 934(Pt 1):39-75
• Editor(s):
  Yan Q
• Federal Fiscal Year:
  2012
• NORA Priority Area:
  Services
• Peer Reviewed:
  False
• Part Number:
  1
• Source Full Name:
  Methods in Molecular Biology. Psychoneuroimmunology: Methods and Protocols
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2a41463ba7a2d10ae8ed8a64eabad86a1372d1cc9ad61267bdde75692c7cd94e57fe265abeba83cba469658f2054880417b908919b9cd4835818d7ac3f27d764
• Download URL:
  https://stacks.cdc.gov/view/cdc/194044/cdc_194044_DS1.pdf
• File Type:
  [PDF - 530.47 KB ]