Detection of polycyclic aromatic hydrocarbons (PAHS) in skin wipe samples of automotive mechanic. trainees

Details

• Personal Author:
  Booth-Jones A ; Neumeister, Charles E. ; Talaska G
• Description:
  Epidemiologic evidence suggests that automobile and truck mechanics are at increased risk of bladder cancer. For mechanics, used gasoline engine oil (UGEO) is a major occupational exposure. UGEOs contain polycyclic aromatic hydrocarbons (PAHs) formed during combustion in engine operation. Because these PAHs have low volatility, mechanics have potential dermal exposure. Many PAHs found in UGEO are known or probable carcinogens. The purpose of this study was to determine whether PAHs were detected in skin wipe samples of automotive mechanic trainees. Sixty-nine participants were enrolled from vocational schools in Ohio and Kentucky. Participants completed an informed consent; 36 were included in the intervention group and were provided with training and special cleansers; and 33 were placed in the nonintervention group. Skin wipe samples were collected by filter paper after participants massaged com oil into their hands. Successive skin wipe samples were taken from those in the intervention group after the intervention was in place. Samples were extracted by ultrasonification in acetonitrile, filtered, and stored until analysis. Sixteen model PAHs measured by fluorescence and UV detectors were naphthalene, acenaphthylene, acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene (FLUOR), pyrene, benz[a] anthracene (BAA), chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a] pyrene (BAP), dibenz[a.,h] anthracene (DAHA), benzo[ghi]perylene, and indeno[1,2,3-cd]pyrene (lNDENO). Eighty-one percent of those in the intervention group provided at least two skin-wipe samples. Measurable amounts of PAHs were detected in 90% of the samples. The concentrations of PAHs ranged from 54.51 microg/microL to 0.18 microg/microL for FLUOR, BAA, BAP, DAHA, and INDENO, which are carcinogens. Mean levels of BAP and DAHA were 4.63 microg/microL and 1.88 microg/microL, respectively; more than 13 participants had levels above these mean values. This study shows that PAHs from UGEO are present in hand-wipe samples of automotive trainees. Excess PAH exposure is hazardous, and interventions should be designed to reduce contact. [Description provided by NIOSH]
• Subjects:
  Automobiles Benzopyrenes Carcinogens Epidemiology Hazardous Substances Hydrocarbons Naphthalenes Neoplasms Occupational Exposure Occupational Health Petroleum Polycyclic Aromatic Hydrocarbons Safety Skin Skin Absorption Staff Development Urogenital Diseases Urogenital System

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• Keywords:
  Anthracenes Automobile-repair-shops Automotive-industry Benzanthracenes Bladder-cancer Cancer Chrysenes Combustion-engines Combustion-products Employee-exposure Exposure-levels Fluorenes Fluoroanthrenes Hazardous-materials Health-hazards Humans Mechanics Motor-vehicles Oils Petroleum-oils Phenanthrenes Polycyclic-aromatic-hydrocarbons Sampling Skin-absorption Skin-exposure Training

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• Publisher:
  American Industrial Hygiene Association
• Document Type:
  Text
• Genre:
  Abstract or Summary
• Place as Subject:
  Florida ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DPSE - Division of Physical Sciences and Engineering
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  47
• NIOSHTIC Number:
  nn:20041454
• Citation:
  American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida. Fairfax, VA: American Industrial Hygiene Association, 2000 May; :47
• CAS Registry Number:
  Acenaphthene (CAS RN 83-32-9) ; Acenaphthylene (CAS RN 208-96-8) ; Acetonitrile (CAS RN 75-05-8) ; Anthracene (CAS RN 120-12-7) ; Benz[e]acephenanthrylene (CAS RN 205-99-2) ; Benzanthracene (CAS RN 56-55-3) ; Benzo[a]pyrene (CAS RN 50-32-8) ; Benzo[ghi]perylene (CAS RN 191-24-2) ; Benzo[k]fluoranthene (CAS RN 207-08-9) ; Chrysene (CAS RN 218-01-9) ; Dibenz[a,h]anthracene (CAS RN 53-70-3) ; Fluoranthene (CAS RN 206-44-0) ; Fluorene (CAS RN 86-73-7) ; Indeno[1,2,3-cd]pyrene (CAS RN 193-39-5) ; Naphthalene (CAS RN 91-20-3) ; Phenanthrene (CAS RN 85-01-8) ; Pyrene (CAS RN 129-00-0)
• Federal Fiscal Year:
  2000
• Peer Reviewed:
  False
• Source Full Name:
  American Industrial Hygiene Conference and Exposition, May 20-25, 2000, Orlando, Florida
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:c85711d296010aea74690b7748360b5c298bc826698a28a90626711f60efa389601ed9eef52faa0d8412937b00ad951cff58bc60209055d2af5a9b08086e92a6
• Download URL:
  https://stacks.cdc.gov/view/cdc/194025/cdc_194025_DS1.pdf
• File Type:
  [PDF - 1.01 MB ]