Epidemiological aspects of occupational lead poisoning

Details

• Personal Author:
  Baker, Edward L. Jr. ; Landrigan, Philip J.
• Description:
  In recent years a major concern in occupational medicine has been to define the toxicity of lead at lower levels of exposure. Investigations conducted since 1970 have demonstrated that lead causes hematologic, neurologic, and renal impairment in lead workers at exposure levels that previously were considered to be safe. In this report the authors describe three recent epidemiological studies of occupational lead exposure. Their purpose in each instance was to evaluate dose-response relationships between blood lead levels and lead toxicity, particularly at lower levels of occupational lead exposure. In this study evidence was found for clinical, hematological, neurological and renal impairment in lead workers many of whom had blood lead levels between 40 and 80 gu/dl. Such findings suggest that blood lead levels in lead workers should not exceed 40 ug/dl, a value already more than two standard deviations above the mean for adult males in the United States. [Description provided by NIOSH]
• Subjects:
  Blood Epidemiology Hazardous Substances Hematologic Tests Kidney Diseases Lead Men Occupational Health Safety Urogenital Diseases Urogenital System

  More +
• Keywords:
  Blood-cells Blood-samples Blood-tests Exposure-levels Humans Kidney-disorders Kidney-function Kidneys Lead-compounds Metallurgy Physiopathology Renal-toxicity Toxic-effects

  More +
• ISSN:
  0387-821X
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; Massachusetts ; North Carolina ; Ohio ; OSHA Region 1 ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; OD - Office of the Director
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  145-155
• Volume:
  5
• NIOSHTIC Number:
  nn:20041026
• Citation:
  J UOEH 1983 Mar; 5(Suppl):145-155
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  1983
• Peer Reviewed:
  False
• Source Full Name:
  Journal of University of Occupational and Environmental Health
• Supplement:
  S
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:567a01afe8202215da9362156a89f527fbda9ed4c8f9e09074434158f715fafef2ecdd7ed6d2894e63182332ea4deecff843dede021de463d5237d4d32276e5f
• Download URL:
  https://stacks.cdc.gov/view/cdc/193697/cdc_193697_DS1.pdf
• File Type:
  [PDF - 259.19 KB ]