Reproductive hormones and interleukin-6 in serious leisure male athletes

Details

• Personal Author:
  Fitzgerald LZ ; Kesner JS ; Robbins WA ; Xun L
• Description:
  Lifestyles associated with different types and intensities of exercise result in improved health including positive changes in chronic low-grade inflammatory biomarkers. Alternatively, some forms of exercise adversely affect reproductive health of men, including changes in circulating reproductive hormones. To explore the associations between exercise intensity and circulating levels of reproductive hormones, and inflammatory analytes in serious leisure athletes (triathletes and cyclists) and recreational athletes. Male athletes 18-60 years old, 16 triathletes, 46 cyclists and 45 recreational athletes, were recruited to provide plasma for the measurement of total testosterone, estradiol, follicular stimulating hormone, luteinizing hormone (LH), sex hormone-binding globulin (SHBG), cortisol, interleukin-6 (IL-6), and interleukin-1β (IL-1β) levels, and calculation of free androgen index (FAI) and the estradiol:SHBG ratio (ESR). Plasma estradiol concentrations were more than two times higher in cyclists than in triathletes and recreational athletes (p < 0.01). Testosterone levels were also higher in cyclists than recreational athletes (p < 0.01), but not significantly different from triathletes. SHBG levels were higher in triathletes and cyclists than in recreational athletes (p < 0.01). LH levels were lower in cyclists than in recreational athletes (p < 0.05). IL-6 and IL-1β levels were each two times lower in triathletes than in cyclists (p < 0.05) and IL-6 levels were lower in cyclists than in recreational athletes (p < 0.01). IL-1β levels were two times lower in triathletes than in cyclists (p < 0.05). Circulating estradiol and testosterone levels were elevated in serious leisure male cyclists. This effect is discussed in light in the absence of a substantial concomitant change in gonadotropin levels and other variables. [Description provided by NIOSH]
• Subjects:
  Athletes Endocrine System Men Occupational Health Safety Urogenital System
• Keywords:
  Androgenic-hormones Author Keywords: Estradiol Bicycles Cytokines Gonadotropic-hormones Hormone-activity Hormones Interleukin Physical-exercise Reproductive-effects Reproductive-system Reproductive Hormones Serious Leisure Athletes Testosterone

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• ISSN:
  1439-6319
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  112
• Issue:
  11
• NIOSHTIC Number:
  nn:20040817
• Citation:
  Eur J Appl Physiol 2012 Nov; 112(11):3765-3773
• Contact Point Address:
  L. Z. FitzGerald, UCLA School of Nursing, 700 Tiverton Avenue, Factor Building 5-137, Los Angeles, CA 90095, USA
• Email:
  tzger@sonnet.ucla.edu
• Federal Fiscal Year:
  2013
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Performing Organization:
  University of California Los Angeles
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  European Journal of Applied Physiology
• End Date:
  20270630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:914e8d7812efcabbbfc1074889387d43b44b5bfa9f5a2e6f82b70ac9cfb4c9ea012ceb5d45e60376ab07ff1b1f6e7c70151f5b13611043a3911fed3a7efc1c1a
• Download URL:
  https://stacks.cdc.gov/view/cdc/193546/cdc_193546_DS1.pdf
• File Type:
  [PDF - 331.43 KB ]