This criteria document recommends revised standards for occupational exposure to elemental arsenic (7440382) and all of its inorganic compounds, including arsine (7784421) and lead-arsenate (7645252) in the workplace air and by skin exposure. Standards cover: environmental (workplace air); medical surveillance; posting of hazardous areas; personal protective equipment and work clothing; informing employees of hazards; work practices; sanitation practices; and monitoring and record keeping. The discussion of biologic effect on humans presents case histories of poisoning and dermatitis, and epidemiologic studies. Data are given from oral and inhalation animal studies of toxicity and carcinogenicity. Air sampling techniques and analytical methods for determining arsenic in urine and in air are described. Required information for material safety data sheet is given.

Guidelines and Recommendations