Body mass index versus dual energy x-ray absorptiometry-derived indexes: predictors of cardiovascular and diabetic disease risk factors

Details

• Personal Author:
  Andrew, Michael E. ; Burchfiel CM ; Sharp DS ; Violanti JM ; Wactawski-Wende J
• Description:
  OBJECTIVES: The body mass index (BMI), a ratio of weight/height(2), dominates estimation of adiposity in population studies. BMI, however, does not distinguish among fat, muscle, or bone mass. Accordingly, its usage to assess and manage obesity in the population is limited. This study compares the use of BMI with direct measures of fat- and lean-mass to predict established cardiovascular and diabetes risk factors: blood pressure, lipids, and glucose. METHODS: The entire Buffalo Police Department was the object of recruitment to a baseline study of physiological and psychological stress. Four hundred nine officers constitute the sample for this analysis. Regression methods focusing on explained variance in blood pressure, high density lipoprotein (HDL) cholesterol, and blood glucose compare the use of BMI to that of fat- and lean-mass indexes derived from dual energy X-ray absorptiometry (DEXA). RESULTS: DEXA indexes explain 1.6%-3.3% (P < 0.05, all risk factors) more variance than BMI. Fat mass drives the association for blood pressure, trunk lean mass for HDL cholesterol, and both for blood glucose. High degrees of multicollinearity complicate interpretation of predictive models jointly containing BMI and DEXA indexes. CONCLUSIONS: In police officers, DEXA indexes are better predictors of cardiovascular disease and diabetes risk factors. However, populations with different distributions of fitness, diet, and health conditions may demonstrate different features. In contrast to BMI, DEXA-derived measurements suggest avenues to explore metabolic processes, which relate to an index's underlying association with risk and may suggest more effective intervention strategies. [Description provided by NIOSH]
• Subjects:
  Absorptiometry, Photon Body Weight Cardiovascular Diseases Cardiovascular System Diet Energy Metabolism Law Enforcement Occupational Health Radiography Safety
• Keywords:
  Absorptiometry BCOPS Body Weight Cardiovascular Disease Metabolism Obesity Police Officers X-ray-absorption
• ISSN:
  1042-0533
• Document Type:
  Text
• Funding:
  Contract ; Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2 ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  400-405
• Volume:
  24
• Issue:
  4
• NIOSHTIC Number:
  nn:20040304
• Citation:
  Am J Hum Biol 2012 Jul/Aug; 24(4):400-405
• Contact Point Address:
  Dan S. Sharp, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, MS4020, Morgantown, WV 26505, USA
• Email:
  DSharp@cdc.gov
• Federal Fiscal Year:
  2012
• NORA Priority Area:
  Services ; Public Safety
• Performing Organization:
  State University of New York at Buffalo
• Peer Reviewed:
  True
• Start Date:
  20100901
• Source Full Name:
  American Journal of Human Biology
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4245da9aa123dce46383e5ac5b1d05e1b6adf5860e90fff7445e5fac7127f6f9a06f44f64cfa67457e9eb1d1e56cbc77991925f1b5b57bb2cbef65ab78f23acb
• Download URL:
  https://stacks.cdc.gov/view/cdc/193234/cdc_193234_DS1.pdf
• File Type:
  [PDF - 197.79 KB ]