Association between cleaning-related chemicals and work-related asthma and asthma symptoms among healthcare professionals

Details

• Personal Author:
  Arif AA ; Delclos GL
• Description:
  OBJECTIVES: Work-related asthma (WRA) is an important public health problem affecting one quarter of adults with asthma. Although cleaning substances are routinely used in hospitals, few studies have addressed their potential adverse respiratory health effects on healthcare professionals (HCPs). This study attempts to identify relationship between work-related exposure to cleaning-related chemicals and development of WRA among HCPs. METHODS: Of 5600 HCPs surveyed, 3650 responded to a validated questionnaire about their occupation, asthma diagnosis, variability of asthma symptoms at and away from work, and exposure to individual cleaning substances. Workplace asthma was defined as a categorical variable with four mutually exclusive categories: work-related asthma symptoms (WRAS), work-exacerbated asthma (WEA), occupational asthma (OA) and none. Multivariable logistic regression analysis was used to evaluate the association between self-reported use of cleaning substances and asthma outcomes among HCPs. RESULTS: Prevalences of WRAS, WEA and OA were 3.3%, 1.1% and 0.8%, respectively. The prevalence estimates were generally higher among female than male HCPs. The odds of WRAS and WEA increased in a dose-dependent manner for exposure in the longest job to cleaning agents and disinfectants/sterilants, respectively. For exposure in any job, the odds of WRAS were significantly elevated for both factor 1 (bleach, cleaners/abrasives, toilet cleaners, detergents and ammonia) and factor 2 (glutaraldehyde/ortho-phtaldehyde, chloramines and ethylene oxide). Significantly elevated odds of WEA were observed for exposure to bleach, factor 2 and formalin/formaldehyde. Exposure to chloramines was significantly associated with an almost fivefold elevated odds of OA. CONCLUSIONS: HCPs are at risk of developing WRA from exposure to cleaning substances. [Description provided by NIOSH]
• Subjects:
  Detergents Epidemiology Health Care Facilities Workforce And Services Health Personnel Irritants Lung Lung Diseases Men Occupational Health Respiratory System Respiratory Tract Diseases Safety Surveys And Questionnaires Women

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• Keywords:
  Breathing Health-care Health-care-facilities Health-care-personnel Housekeeping-products Humans Medical-facilities Medical-personnel Pulmonary-disorders Pulmonary-function Pulmonary-system Pulmonary-system-disorders Questionnaires Respiration Respiratory-infections Respiratory-irritants Respiratory-system-disorders Statistical-analysis

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• ISSN:
  1351-0711
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  North Carolina ; OSHA Region 4 ; OSHA Region 6 ; Texas
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  35-40
• Volume:
  69
• Issue:
  1
• NIOSHTIC Number:
  nn:20040294
• Citation:
  Occup Environ Med 2012 Jan; 69(1):35-40
• Contact Point Address:
  Ahmed A Arif, Associate Professor, UNC Charlotte, Department of Public Health Sciences, CHHS 429, 9201 University City Blvd, Charlotte, NC 28223
• Email:
  aarif@uncc.edu
• Federal Fiscal Year:
  2012
• Performing Organization:
  University of Texas, Health Science Center, Houston
• Peer Reviewed:
  True
• Start Date:
  20010930
• Source Full Name:
  Occupational and Environmental Medicine
• End Date:
  20050929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a2229d0ba236901f44a644c2e23675cfe783caff0c4e56bc3b1641ac5a70f73f71223d9c307092a1238c9ed9b296bc86ae12a482fbd14c48ad64a54eba5c6d02
• Download URL:
  https://stacks.cdc.gov/view/cdc/193227/cdc_193227_DS1.pdf
• File Type:
  [PDF - 352.34 KB ]