Risk and significance of chest radiograph and pulmonary function abnormalities in an elderly cohort of former nuclear weapons workers

Details

• Personal Author:
  Fuortes LJ ; Hartley PG ; Lourens S ; Mikulski MA ; Sanderson, Wayne T. ; Sprince NL ; Wang K ; Worden NE
• Description:
  OBJECTIVE: To estimate prevalence and risk factors for International Labour Organization radiographic abnormalities, and assess relationship of these abnormalities with spirometry results in former Department of Energy nuclear weapons workers. METHODS: Participants were offered chest x-ray (CXR) and lung function testing. Three occupational medicine physicians read CXRs. RESULTS: Forty-five (5.9%) of 757 screened workers were found to have isolated parenchymal abnormalities on CXR and this rate is higher than that in many Department of Energy studies. Parenchymal and pleural and isolated pleural abnormalities were found in 19 (2.5%) and 37 (4.9%) workers, respectively, and these rates are lower than those in other Department of Energy studies to date. Lung function impairment was associated with radiographic abnormalities. CONCLUSIONS: This study found an elevated rate of parenchymal abnormalities compared to other DoE populations but the effect of age or other causes could not be ruled out. [Description provided by NIOSH]
• Subjects:
  Asbestos Beryllium Epidemiology Inorganic Chemicals Lung Nitrates Occupational Health Radiation Radiography Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety Workplace

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• Keywords:
  Asbestos-fibers Barium-compounds Beryllium-compounds Exposure-levels Exposure-limits Ionizing-radiation Lung-function Nuclear-hazards Nuclear-radiation Pneumoconiosis Pulmonary-function Pulmonary-system Pulmonary-system-disorders Radiographic-analysis Radionuclides Risk-factors Work-environment Workers X-ray-diagnosis

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• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Iowa ; Kentucky ; OSHA Region 4 ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  53
• Issue:
  9
• NIOSHTIC Number:
  nn:20040286
• Citation:
  J Occup Environ Med 2011 Sep; 53(9):1046-1053
• Contact Point Address:
  Marek Mikulski, MD, MPH, PhD, The University of Iowa, 2213 Westlawn, Iowa City, IA 52242
• Email:
  marek-mikulski@uiowa.edu
• CAS Registry Number:
  Asbestos (CAS RN 1332-21-4) ; Barium (CAS RN 7440-39-3) ; Barium nitrate (CAS RN 10022-31-8) ; Beryllium (CAS RN 7440-41-7)
• Federal Fiscal Year:
  2011
• Performing Organization:
  University of Iowa
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20290630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0eb233434078cdf46209651760f938ccdbb0c4150d459d32187a0e09df4d70d8b93689265533643d414fa1b6fd364135f389002ea1d5f16edf14f3d51c26be6a
• Download URL:
  https://stacks.cdc.gov/view/cdc/193219/cdc_193219_DS1.pdf
• File Type:
  [PDF - 135.91 KB ]