Pathogenesis and disease mechanisms of occupational asthma

Details

• Personal Author:
  Bernstein DI ; Lummus ZL ; Wisnewski AV
• Description:
  Occupational asthma (OA) is one of the most common forms of work-related lung disease in all industrialized nations. The clinical management of patients with OA depends on an understanding of the multifactorial pathogenetic mechanisms that can contribute to this disease. This article discusses the various immunologic and nonimmunologic mechanisms and genetic susceptibility factors that drive the inflammatory processes of OA. [Description provided by NIOSH]
• Subjects:
  Asthma Asthma, Occupational Genetics Immune System Lung Diseases Occupational Health Pathology Respiratory Tract Diseases Safety
• Keywords:
  Airway Hyperresponsiveness Airway Remodeling Author Keywords: Occupational Asthma Bronchial-asthma Genetic-factors Genetic Susceptibility Immune-reaction Immune Mechanisms Immunology Lung-disorders Oxidative Stress Pathogenesis Pulmonary-system-disorders Respiratory-system-disorders Workplace Allergens

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• ISSN:
  0889-8561
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Connecticut ; Ohio ; OSHA Region 1 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  31
• Issue:
  4
• NIOSHTIC Number:
  nn:20040251
• Citation:
  Immunol Allergy Clin North Am 2011 Nov; 31(4):699-716
• Contact Point Address:
  David I. Bernstein, MD, Division of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, 3255 Eden Avenue, Cincinnati, OH 45267-0563, USA
• Email:
  Bernstdd@ucmail.uc.edu
• Federal Fiscal Year:
  2012
• Performing Organization:
  University of Cincinnati
• Peer Reviewed:
  True
• Start Date:
  20060901
• Source Full Name:
  Immunology and Allergy Clinics of North America
• End Date:
  20180831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:245714258b6886460d836ac7f8b2179663ba108d5dd53d8a7fc99f18ce75a9eda351c33d46ae6a61216c7af15f56776f8bb31003c337d7428065224166118ef6
• Download URL:
  https://stacks.cdc.gov/view/cdc/193192/cdc_193192_DS1.pdf
• File Type:
  [PDF - 146.59 KB ]