Informatics and standards for nanomedicine technology

Details

• Personal Author:
  Baker NA ; Freund ET ; Fritts M ; Gaheen S ; Harper SL ; Hoover, Mark D. ; Klaessig F ; Klemm JD ; Paik DS ; Reznik-Zellen R ; Stokes TH ; Thomas DG
• Description:
  There are several issues to be addressed concerning the management and effective use of information (or data), generated from nanotechnology studies in biomedical research and medicine. These data are large in volume, diverse in content, and are beset with gaps and ambiguities in the description and characterization of nanomaterials. In this work, we have reviewed three areas of nanomedicine informatics: information resources; taxonomies, controlled vocabularies, and ontologies; and information standards. Informatics methods and standards in each of these areas are critical for enabling collaboration; data sharing; unambiguous representation and interpretation of data; semantic (meaningful) search and integration of data; and for ensuring data quality, reliability, and reproducibility. In particular, we have considered four types of information standards in this article, which are standard characterization protocols, common terminology standards, minimum information standards, and standard data communication (exchange) formats. Currently, because of gaps and ambiguities in the data, it is also difficult to apply computational methods and machine learning techniques to analyze, interpret, and recognize patterns in data that are high dimensional in nature, and also to relate variations in nanomaterial properties to variations in their chemical composition, synthesis, characterization protocols, and so on. Progress toward resolving the issues of information management in nanomedicine using informatics methods and standards discussed in this article will be essential to the rapidly growing field of nanomedicine informatics. [Description provided by NIOSH]
• Subjects:
  Chemistry Occupational Health Quality Control Safety
• Keywords:
  Biomedical-engineering Chemical-analysis Chemical-composition Chemical-properties Data-processing Health-standards Information-processing Information-retrieval-systems Information-systems Medical-research Medical-sciences Nanotechnology Quality-standards Standards

  More +
• ISSN:
  1939-0041
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  California ; Georgia ; Maryland ; Massachusetts ; Oregon ; OSHA Region 1 ; OSHA Region 10 ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 9 ; Pennsylvania ; Washington ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  3
• Issue:
  5
• NIOSHTIC Number:
  nn:20040229
• Citation:
  Wiley Interdiscip Rev. Nanomed Nanobiotechnol 2011 Sep-Oct; 3(5):511-532
• Contact Point Address:
  Nathan A. Baker, Pacific Northwest National Laboratory, Richland, WA, USA
• Email:
  nathan.baker@pnl.gov
• Federal Fiscal Year:
  2011
• NORA Priority Area:
  Manufacturing
• Peer Reviewed:
  True
• Source Full Name:
  Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:268dcf06e7ce3ad002c92db20ca6e340f05f9361bbb7da876b70446e039c86ed4be0440d5aa39ceb40cd3b612e152e8851d4acc3108bb535dffc1be45df8a087
• Download URL:
  https://stacks.cdc.gov/view/cdc/193171/cdc_193171_DS1.pdf
• File Type:
  [PDF - 284.16 KB ]