An updated algorithm for estimation of pesticide exposure intensity in the Agricultural Health Study

Details

• Personal Author:
  Alavanja MCR ; Blair, Austin ; Coble J ; Curwin B ; Dosemeci, Mustafa ; Freeman LEB ; Hines CJ ; Hoppin JA ; Lubin JH ; Sandler DP ; Thomas KW
• Description:
  An algorithm developed to estimate pesticide exposure intensity for use in epidemiologic analyses was revised based on data from two exposure monitoring studies. In the first study, we estimated relative exposure intensity based on the results of measurements taken during the application of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) (n = 88) and the insecticide chlorpyrifos (n = 17). Modifications to the algorithm weighting factors were based on geometric means (GM) of post-application urine concentrations for applicators grouped by application method and use of chemically-resistant (CR) gloves. Measurement data from a second study were also used to evaluate relative exposure levels associated with air blast as compared to hand spray application methods. Algorithm modifications included an increase in the exposure reduction factor for use of CR gloves from 40% to 60%, an increase in the application method weight for boom spray relative to in-furrow and for air blast relative to hand spray, and a decrease in the weight for mixing relative to the new weights assigned for application methods. The weighting factors for the revised algorithm now incorporate exposure measurements taken on Agricultural Health Study (AHS) participants for the application methods and personal protective equipment (PPE) commonly reported by study participants. [Description provided by NIOSH]
• Subjects:
  Agriculture Environmental Monitoring Epidemiology Health Care Facilities Workforce And Services Insecticides Occupational Exposure Occupational Health Paint Personal Protective Equipment Safety
• Keywords:
  2,4-D Agglutination Agricultural-chemicals Agricultural-workers Author Keywords: Pesticides Captan Chlorpyrifos Employee-exposure Exposure-assessment Exposure Algorithm Gloves Mathematical-models Medical-monitoring Personal-protective-equipment Pesticides Pesticides-and-agricultural-chemicals Spraying-equipment Sprays Surveillance-programs Worker-health

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• ISSN:
  1660-4601
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; North Carolina ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  8
• Issue:
  12
• NIOSHTIC Number:
  nn:20040207
• Citation:
  Int J Environ Res Public Health 2011 Dec; 8(12):4608-4622
• Contact Point Address:
  Alavanja, MCR (reprint author), NCI, Occupat & Environm Epidemiol Branch, Div Canc Epidemiol & Genet, NIH, DHHS, 1620 Execut Blvd, Rockville, MD 20892 USA
• CAS Registry Number:
  (2,4-Dichlorophenoxy)acetic acid (CAS RN 94-75-7) ; Captan (CAS RN 133-06-2) ; Chlorpyrifos (CAS RN 2921-88-2)
• Federal Fiscal Year:
  2012
• NORA Priority Area:
  Agriculture, Forestry and Fishing
• Peer Reviewed:
  True
• Source Full Name:
  International Journal of Environmental Research and Public Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1f0d625968af0dee3d0f66bc55e2d1e162539daf2eea7eebc046ddadcddc03bf1eec8e75f07feeecaa302e432d044b2e1191873708cf6a359b6fab107038d96d
• Download URL:
  https://stacks.cdc.gov/view/cdc/193155/cdc_193155_DS1.pdf
• File Type:
  [PDF - 322.65 KB ]