Inter-rater reliability of assessed prenatal maternal occupational exposures to solvents, polycyclic aromatic hydrocarbons, and heavy metals
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2011/12/01
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Description:Because direct measurements of past occupational exposures are rarely available in population-based case-control studies, exposure assessment of job histories by multiple expert raters is frequently used; however, the subjective nature of this method makes measuring reliability an important quality control step. We evaluated inter-rater reliability of 7729 retrospective jobs reported in the National Birth Defects Prevention Study. Jobs were classified as exposed, unexposed, or exposure unknown by two independent industrial hygienists; exposed jobs were further evaluated for intensity, frequency, and routes. Exposure prevalence ranged from 0.1-9.8 percent. Inter-rater reliability for exposure (yes/no), assessed by kappa coefficients, was fair to good for cadmium (kappa = 0.46), chlorinated solvents (kappa = 0.59), cobalt (kappa = 0.54), glycol ethers (kappa = 0.50), nickel compounds (kappa = 0.65), oil mists (kappa = 0.63), and Stoddard Solvent (kappa = 0.55); PAHs (kappa = 0.24) and elemental nickel (kappa = 0.37) had poor agreement. After a consensus conference resolved disagreements, an additional 4962 jobs were evaluated. Inter-rater reliability improved or stayed the same for cadmium (kappa = 0.51), chlorinated solvents (kappa = 0.81), oil mists (kappa = 0.63), PAHs (kappa = 0.52), and Stoddard solvent (kappa =0.92) in the second job set. Inter-rater reliability varied by exposure agent and prevalence, demonstrating the importance of measuring reliability in studies using a multiple expert rater method of exposure assessment. [Description provided by NIOSH]
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ISSN:1545-9624
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Place as Subject:Georgia ; Ohio ; OSHA Region 10 ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; Virginia ; Washington
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Volume:8
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Issue:12
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NIOSHTIC Number:nn:20039964
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Citation:J Occup Environ Hyg 2011 Dec; 8(12):718-728
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Contact Point Address:Carissa M. Rocheleau, National Institute for Occupational Safety and Health, 4676 Columbia Pkwy, MS R-15, Cincinnati, OH 45226
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Email:CRocheleau@cdc.gov
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Federal Fiscal Year:2012
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Performing Organization:Battelle
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Peer Reviewed:True
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Source Full Name:Journal of Occupational and Environmental Hygiene
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Main Document Checksum:urn:sha-512:106a5f5602220092b409b22080a8c19562256c46a5d33ba218845b7b78385ecec13a25e6ce64699af2d6ad24f3c70f51239b72f7b617f07c813cc01a3d1631fb
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