Industrial hygiene assessment of reticuloendotheliosis viruses exposure in the poultry industry

Details

• Personal Author:
  Choi KM ; Johnson ES
• Description:
  OBJECTIVES: Reticuloendotheliosis viruses (REV) are a group of retroviruses like avian leukosis/sarcoma viruses (ALSV) that naturally infect and cause cancers in chickens. We recently found that ALSV antibody levels were associated with job tasks in the poultry industry. The objectives of this study are to examine whether a similar association can be found with REV antibody levels and to examine the correlation between REV and ALSV antibody levels. METHODS: Relative risk was estimated comparing REV antibody levels of 45 poultry workers with those of 44 controls. The expected mean antibody level was predicted for the association with employment by a generalized linear model. Correlation coefficient was measured between ALSV and REV antibody levels. RESULTS: REV antibody levels were significantly higher in poultry workers than in control subjects and were associated with gender and employment conditions, especially employment duration. The relative risk was significantly higher for some job categories. A significant correlation was observed between REV and ALSV antibody levels, which was strong among poultry workers, but weak among the control subjects. CONCLUSION: Antibody levels can be validly used to identify certain job tasks associated with high risk of exposure to REV in the workplace, and the practical implication is recommendations for protection at these job tasks. Importantly, in situations where there is exposure to multiple pathogens in the workplace, the analysis of antibody levels of one pathogen may sufficiently represent exposure to the other correlated pathogens. This suggested exposure assessment may hold true for pathogens with a similar route of transmission. [Description provided by NIOSH]
• Subjects:
  Animals Antibodies Carcinogens Cardiovascular Diseases Cardiovascular System Environmental Monitoring Food Handling Food Industry Immune System Livestock Lung Lung Diseases Mortality Neoplasms Occupational Health Respiratory System Respiratory Tract Diseases Risk Assessment Safety Workplace

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• Keywords:
  Animal-products-workers Author Keywords: Exposure Assessment Cancer Carcinogenesis Cardiovascular-system-disease Disease-incidence Disease-transmission Exposure-assessment Immune-system-disorders Immunologic-disorders Lung-cancer Lung-disease Lung-disorders Meat-handlers Microbial Agents Mortality-data Multiple Pathogens Pathogenicity Poultry Poultry-industry Poultry-workers Poultry Workers Pulmonary-system Pulmonary-system-disorders Respiratory-system-disorders Risk-analysis Slaughterhouses Work-areas Work-operations Work-performance Worker-health Workplace-studies Zoonoses

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• ISSN:
  0340-0131
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 6 ; Texas
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  375-382
• Volume:
  84
• Issue:
  4
• NIOSHTIC Number:
  nn:20039016
• Citation:
  Int Arch Occup Environ Health 2011 Apr; 84(4):375-382
• Contact Point Address:
  KM Choi, Department of Environmental and Occupational Health Sciences, University of North Texas, Health Science Center, School of Public Health, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107
• Email:
  kchoi@hsc.unt.edu
• Federal Fiscal Year:
  2011
• Performing Organization:
  University of North Texas
• Peer Reviewed:
  True
• Start Date:
  20050901
• Source Full Name:
  International Archives of Occupational and Environmental Health
• End Date:
  20080430
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:10d7d93319d066c2dcea193d851db29d458abeaa4d6853d817127ee2fa59a97a8f6310518df0bb5af141610848da1dd197de0abaa7d3eb8c0f9c85e7ecbd365b
• Download URL:
  https://stacks.cdc.gov/view/cdc/192514/cdc_192514_DS1.pdf
• File Type:
  [PDF - 222.78 KB ]