Preparation and characterization of polymerizable hindered amine-based antimicrobial fibrous materials

Details

• Personal Author:
  Sun Y ; Yao J
• Description:
  A polymerizable hindered amine-based antimicrobial fibrous material was successfully prepared by grafting 2,2,6,6-tetramethyl-4-piperdyl methacrylate onto cotton fabrics and sequentially chlorinating the grafted materials with diluted sodium hypochlorite solutions. The effects of grafting conditions on the grafting reactions were investigated. The resultant polymeric amine N-halamine fibrous material provided a total kill of 106-107 cfu/mL of Escherichia coli (ATCC 15597), Staphylococcus epidermidis (ATCC 35984), and Staphylococcus aureus (ATCC 6538) within 30 min. Autoclave treatment and TGA study showed that the covalently bound chlorines have excellent thermal and hydrolytic stabilities. The antimicrobial function was both durable and rechargeable. These properties make the new fibrous materials attractive candidates for a broad range of applications. [Description provided by NIOSH]
• Subjects:
  Anti-Bacterial Agents Antibodies Antigens Biochemistry Biological Products Microbiology Occupational Health Particulate Matter Safety
• Keywords:
  Antibacterial-agents Antibiotics Antibody-response Antifungals Antisepsis Bactericides Biochemical-analysis Biocides Biological-effects Biological-material Fibrous-bodies Microorganisms

  More +
• ISSN:
  0888-5885
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 8 ; South Dakota
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  47
• Issue:
  16
• NIOSHTIC Number:
  nn:20038900
• Citation:
  Ind Eng Chem Res 2008 Aug; 47(16):5761-6344
• Contact Point Address:
  Yuyu Sun, Department of Macromolecular Science, Fudan University, Shanghai, China, 200433
• Email:
  yuyu.sun@usd.edu
• Federal Fiscal Year:
  2008
• Performing Organization:
  University of South Dakota
• Peer Reviewed:
  False
• Start Date:
  20050401
• Source Full Name:
  Industrial & Engineering Chemistry Research
• End Date:
  20080331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:26a6bbb8d3e12f0d46a99adfc5093504342f6772dba4e7d4cbf2316bb058bbb51a8a6103b66a09ad697c5a98362a41adc06d9011b01ba6fc2b696928120fd83a
• Download URL:
  https://stacks.cdc.gov/view/cdc/192434/cdc_192434_DS1.pdf
• File Type:
  [PDF - 153.50 KB ]