Evaluation of exposures to healthcare personnel from cisplatin during a mock interperitoneal operation

Details

• Personal Author:
  Burr, Gregory A. ; Couch, James R.
• Description:
  The HHE Program responded to a request concerning healthcare personnel's potential exposures to cisplatin, a chemotherapy drug, during a newly proposed medical procedure. Program investigators took wipe samples and area and personal breathing zone samples for cisplatin during pharmacy preparation, a mock interperitoneal procedure, cleaning of the operating room, and sterilization of the equipment. Investigators also checked to see if the gloves worn by employees protected them from cisplatin by analyzing cotton gloves that were worn beneath their chemotherapy-approved gloves. Cisplatin was not found in any of the area or personal breathing zone air samples or on any of the cotton glove samples. Investigators did find cisplatin on one of 15 wipe samples collected during this investigation. This wipe sample was taken from the operating room floor after the mock procedure but before the room was cleaned. No cisplatin was found at the same location after the operating room had been cleaned. Program investigators recommended that hospital management require employees to wear two pairs of chemotherapy protective gloves. It was also recommended that managers train employees on the importance of minimizing cisplatin spills and splashes and how to properly clean up such incidents. The final report is available at https://www.cdc.gov/niosh/hhe/reports/pdfs/2009-0121-3106.pdf. [Description provided by NIOSH]
• Subjects:
  Drug Therapy Health Personnel Neoplasms Occupational Health Personal Protective Equipment Protective Clothing Safety
• Keywords:
  Chemotherapy Drug-therapy Gloves Health-care-personnel Medical-personnel Medical-treatment Personal-protection Protective-clothing Work-practices
• ISSN:
  1077-3525
• Document Type:
  Text
• Genre:
  Abstract or Summary
• Place as Subject:
  Nevada ; Ohio ; OSHA Region 5 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  16
• Issue:
  4
• NIOSHTIC Number:
  nn:20038228
• Citation:
  Int J Occup Environ Health 2010 Oct-Dec; 16(4):540
• CAS Registry Number:
  Cisplatin (CAS RN 15663-27-1)
• Federal Fiscal Year:
  2011
• NORA Priority Area:
  Services
• Peer Reviewed:
  False
• NAICS and SIC Codes:
  622110 - General Medical and Surgical Hospitals - (NAICS)
• Source Full Name:
  International Journal of Occupational and Environmental Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:967647691f4a215953ba500c65c0456a7b24175f2f724fc337b01a46f15e0d255ecc6131f99e55526f7a464d981064f121582ee0ea216cf1f1131cdcd84addeb
• Download URL:
  https://stacks.cdc.gov/view/cdc/192001/cdc_192001_DS1.pdf
• File Type:
  [PDF - 149.23 KB ]