Endothelial function, a biomarker of subclinical cardiovascular disease, in urban police officers

Details

• Personal Author:
  Andrew, Michael E. ; Burchfiel CM ; Donahue R ; Dorn J ; Joseph PN ; Trevisan M ; Violanti JM
• Description:
  Objective: Police officers were hypothesized to have decreased endothelial function, measured by brachial artery flow-mediated dilation (FMD). Methods: We compared FMD in police officers (n = 261) and a population sample of men and women (n = 229), all from the same geographical region and free of clinical cardiovascular disease (CVD). Results: Compared with the population sample, police officers had significantly increased age-adjusted CVD risk factors (systolic and diastolic blood pressure, total cholesterol, smoking prevalence, and alcohol consumption). Police officers exhibited lower mean FMD after adjustment for age, gender, and traditional CVD risk factors among those aged 55 years or younger (%dilation: police = 5.49%, population = 6.49%; P = 0.04). Conclusions: Police officers exhibited decreased endothelial function (lower FMD) compared with the civilian sample, which was not fully explained by traditional CVD risk factors, suggesting that other pathways may contribute to increased CVD risk in law enforcement work. [Description provided by NIOSH]
• Subjects:
  Biomarkers Cardiovascular Diseases Cardiovascular System Epidemiology Law Enforcement Occupational Health Safety
• Keywords:
  BCOPS Cardiovascular Disease Law Enforcement Police Officers Psychological Responses Stress
• ISSN:
  1076-2752
• Document Type:
  Text
• Funding:
  Grant ; Contract
• Genre:
  Journal Article
• Place as Subject:
  Nevada ; New York ; OSHA Region 2 ; OSHA Region 3 ; OSHA Region 9 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  52
• Issue:
  10
• NIOSHTIC Number:
  nn:20037792
• Citation:
  J Occup Environ Med 2010 Oct; 52(10):1004-1008
• Contact Point Address:
  Parveen Nedra Joseph, PhD, Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road M/S 4050, Morgantown, WV 26505
• Email:
  nedrajoseph@hotmail.com
• Federal Fiscal Year:
  2011
• NORA Priority Area:
  Services ; Public Safety
• Performing Organization:
  State University of New York at Buffalo
• Peer Reviewed:
  True
• Start Date:
  20100901
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• End Date:
  20150831
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:efe3f5f7ed92930040b4fa0e819c022ee7a63dd9bf5dc0bae43ab2f56dcf8b85403d342a850c8e02695fd60984df750e094a6e5a4a070e6f3b367786647f4ed1
• Download URL:
  https://stacks.cdc.gov/view/cdc/191762/cdc_191762_DS1.pdf
• File Type:
  [PDF - 132.19 KB ]