Glove Permeation Tests Using Novel Microchemical Techniques for 2, 4-Dichlorophenoxyacetic Acid (2,4-D) Derivatives

Details

• Personal Author:
  Lin Y-W ; Que Hee SS
• Description:
  The aim was to assess the permeation of different herbicide emulsion concentrate formulations of 2,4-dichlorophenoxyacetic acid (2,4-D) as 60.8 and 83.5% butoxyethyl ester (BEE) and 46.8% dimethyl amine salt (DMAS) through four types of glove materials (lined unsupported nitrile, unlined unsupported butyl, Silver Shield laminate, and Viton). This entailed the development of new microchemical techniques to allow sensitive capillary gas chromatography/mass spectrometry (GC/MS) of the permeated herbicide. The 2,4-D DMAS was esterified to the methyl ester by boron trifluoride-methanol complex with 99.2 +/- 3.7% efficiency using microwave heating to minimize reaction time and to process microsamples. The GC/MS detection limit was 5 ng/ml (ppb) of 2,4-D DMAS in the collection medium. The permeates from the ester formulations were analyzed directly for the ester above the detection limit of 9 ng/ml (ppb) BEE. The permeation investigations utilized the American Society for Testing Materials (ASTM)-type permeation cells with liquid collection media. The results showed that these gloves could provide at least 6 h protection for these formulations. [Description provided by NIOSH]
• Subjects:
  Herbicides Mass Spectrometry Occupational Health Personal Protective Equipment Protective Clothing Safety
• Keywords:
  Gas-chromatography Mass-spectrometry Microchemistry Molecular-structure Personal-protection Protective-clothing Protective-materials
• ISSN:
  0090-4341
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  485-489
• Volume:
  36
• Issue:
  4
• NIOSHTIC Number:
  nn:20031292
• Citation:
  Arch Environ Contam Toxicol 1999 May; 36(4):485-489
• Contact Point Address:
  Department of Environmental Health Sciences and UCLA Center for Occupational and Environmental Health, UCLA School of Public Health, 10833 Le Conte Ave., Los Angeles, California 90095-1772
• CAS Registry Number:
  (2,4-Dichlorophenoxy)acetic acid (CAS RN 94-75-7)
• Federal Fiscal Year:
  1999
• NORA Priority Area:
  Research Tools and Approaches: Intervention Effectiveness Research
• Performing Organization:
  University of California, School of Public Health, Department of Environmental Health Sciences, 10333 Le Conte Avenue, Los Angeles, CA 90024-1772
• Peer Reviewed:
  True
• Start Date:
  19920930
• Source Full Name:
  Archives of Environmental Contamination and Toxicology
• End Date:
  19951130
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:7fe37872504d1171e77bff4e961002a9c52d527a97d3c82e530d6668a7230a733124971a63128fa292f64dd377288e97ed8d43a80da9cdc618d698caa6fb360c
• Download URL:
  https://stacks.cdc.gov/view/cdc/191586/cdc_191586_DS1.pdf
• File Type:
  [PDF - 108.42 KB ]