Exposure Assessment in the National Children’s Study: Introduction

Details

• Personal Author:
  Akland G ; Bahadori T ; Barr DB ; Bradman A ; Fortmann R ; Liu LJ ; Morandi M ; Naeher L ; Needham LL ; O'Rourke MK ; Ozkaynak H ; Quackenboss J ; Ryan PB ; Thomas K ; Wang RY ; Whyatt RM ; Zartarian V
• Description:
  The science of exposure assessment is relatively new and evolving rapidly with the advancement of sophisticated methods for specific measurements at the picogram per gram level or lower in a variety of environmental and biologic matrices. Without this measurement capability, environmental health studies rely on questionnaires or other indirect means as the primary method to assess individual exposures. Although we use indirect methods, they are seldom used as stand-alone tools. Analyses of environmental and biologic samples have allowed us to get more precise data on exposure pathways, from sources to concentrations, to routes, to exposure, to doses. They also often allow a better estimation of the absorbed dose and its relation to potential adverse health outcomes in individuals and in populations. Here, we make note of various environmental agents and how best to assess exposure to them in the National Children's Study--a longitudinal epidemiologic study of children's health. Criteria for the analytical method of choice are discussed with particular emphasis on the need for long-term quality control and quality assurance measures. [Description provided by NIOSH]
• Subjects:
  Environmental Exposure Environmental Health Environmental Monitoring Epidemiology Hypersensitivity Occupational Health Safety Surveys And Questionnaires
• Keywords:
  Allergens Analytical-methods Children Environmental-exposure Environmental-health Environmental-health-monitoring Exposure-assessment Organic-chemicals Questionnaires
• ISSN:
  0091-6765
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Arizona ; Georgia ; OSHA Region 4 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  113
• Issue:
  8
• NIOSHTIC Number:
  nn:20031212
• Citation:
  Environ Health Perspect 2005 Aug; 113(8):1076-1082
• Contact Point Address:
  L.L. Needham, Mailstop F17, 4770 Buford Highway, Atlanta, GA 30341 USA
• Email:
  lneedham@cdc.gov
• Federal Fiscal Year:
  2005
• Performing Organization:
  University of Arizona, Tucson, Arizona
• Peer Reviewed:
  True
• Start Date:
  19950701
• Source Full Name:
  Environmental Health Perspectives
• End Date:
  20060630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:95cd2e437cd090064f33619759b24a9cf5a573dfa8a9ae1f7a71d4294caababe923282949649d0f02216ddbdbbd37a60febcfc91863d512c9dbb354d08b6910d
• Download URL:
  https://stacks.cdc.gov/view/cdc/191527/cdc_191527_DS1.pdf
• File Type:
  [PDF - 110.67 KB ]