Use of Multiple Cause of Death Data in Cancer Mortality Analyses

Details

• Personal Author:
  Richardson DB
• Description:
  Background: In a cancer mortality study, the decision of whether to define a study outcome via underlying cause of death (UCD) or via multiple cause of death (MCD) information may impact relative risk (RR) estimates and associated confidence intervals. Methods: Simple equations are presented that relate RR estimates obtained in a cancer incidence study to the RR estimates obtained in mortality studies using UCD and MCD information. Data from the Surveillance, Epidemiology and End Results program were used to obtain information about the detection and confirmation rates of cancer diagnoses made via UCD. Data from US cause of death data tapes were used to obtain information on the ratio of UCD to MCD listings for cancer outcomes. Numerical examples illustrate the use of these equations. Results: In our examples, the RRs obtained via analyses of MCD were close to those obtained via analyses of UCD (but of greater precision), even when assuming that the confirmation rate of cancer diagnoses made via MCD listing was substantially lower than that of diagnoses made via UCD. Conclusions: These finding are supportive of the use of MCD information in cancer mortality studies. [Description provided by NIOSH]
• Subjects:
  Geology Mining Occupational Health Safety
• Keywords:
  Cancer Cancer-rates Epidemiology Information-retrieval-systems Mortality-data Mortality-rates Occupational-diseases Risk-analysis Surveillance-programs
• ISSN:
  0271-3586
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  North Carolina ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  49
• Issue:
  8
• NIOSHTIC Number:
  nn:20030607
• Citation:
  Am J Ind Med 2006 Aug; 49(8):683-689
• Contact Point Address:
  David B. Richardson, Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7435
• Email:
  david.richardson@unc.edu
• Federal Fiscal Year:
  2006
• NORA Priority Area:
  Research Tools and Approaches: Cancer Research Methods
• Performing Organization:
  University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
• Peer Reviewed:
  True
• Start Date:
  20020930
• Source Full Name:
  American Journal of Industrial Medicine
• End Date:
  20060929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d9d12befb2d6c5c3ee279d4faf65f37be3fd58ea60317bd5f753c1270d765a18515502d4621692a26c743c7205178a6a847b5cbe260439be5271252ec3c76829
• Download URL:
  https://stacks.cdc.gov/view/cdc/191156/cdc_191156_DS1.pdf
• File Type:
  [PDF - 104.70 KB ]