Exhaled Nitric Oxide Measurement in Workers in a Microwave Popcorn Production Plant

Details

• Personal Author:
  Akpinar-Elci, Muge ; Dweik RD ; Elci, Omur Cinar ; Enright, Paul L. ; Kreiss, Kathleen ; Stemple, Kimberly J.
• Description:
  Airways obstruction in microwave-popcorn workers has been attributed to inhalation of flavoring agents. Two former workers at a microwave-popcorn plant were found by lung biopsy to have bronchiolitis obliterans. The study's aim was to determine whether exhaled nitric oxide (FENO) levels were associated with exposure levels, respiratory symptoms, or airways obstruction. A questionnaire, spirometry, and FENO measurements were completed by 135 workers. The FENO levels of workers with high flavoring exposures (n = 107) were compared with those of workers with low exposures (n = 28) and healthy external controls (n = 31). FENO levels were significantly lower in the high-exposure group (p < 0.05). There is no indication that FENO is useful as a marker of lung injury in a flavoring-exposed worker population with a substantial lung disease burden, but the finding of low FENO in the high-exposure group should not be dismissed. [Description provided by NIOSH]
• Subjects:
  Food-Processing Industry Food Additives Food Handling Food Industry Lung Lung Diseases Nitrates Occupational Exposure Occupational Health Radiography Respiratory Function Tests Respiratory System Respiratory Tract Diseases Safety

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• Keywords:
  Airway-obstruction Chest-X-rays Food-additives Food-processing Food-processing-industry Food-processing-workers Lung-disease Occupational-exposure Oxides Pulmonary-disorders Pulmonary-function Pulmonary-system-disorders Respiratory-system-disorders Spirometry

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• ISSN:
  1077-3525
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  106-110
• Volume:
  12
• Issue:
  2
• NIOSHTIC Number:
  nn:20030092
• Citation:
  Int J Occup Environ Health 2006 Apr-Jun; 12(2):106-110
• Contact Point Address:
  National Institute for Occupational Safety and Health, Division of Respiratory Diseases Studies, Field Studies Branch, Mail Stop H-2800, 1095 Willowdale Road, Morgantown, WV 26505
• Email:
  melci@cdc.gov
• CAS Registry Number:
  Nitric oxide (CAS RN 10102-43-9)
• Federal Fiscal Year:
  2006
• Peer Reviewed:
  True
• Source Full Name:
  International Journal of Occupational and Environmental Health
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a4f6f3f8c576aad85928bb06718a7ef9f7e04cb4b6b61ac476e8cab0b66141b12f74d97ff6d82e3f9258a27c7c796d73a86814575f4106e470cc4ec463fe5e2c
• Download URL:
  https://stacks.cdc.gov/view/cdc/190919/cdc_190919_DS1.pdf
• File Type:
  [PDF - 299.36 KB ]