Pesticide Exposure, Host Susceptibility Factors and Risk of Parkinson’s Disease: An Introduction to a Work in Progress

Details

• Personal Author:
  Burmester JK ; Greenlee AR ; Hiner BC
• Description:
  Linking exposures with bio­marker data may provide a clearer understanding of the mechanisms by which agrochemi­cal exposures influence the occurrence of PD and may assist with formulating strategies for reducing adverse health consequences for agricultural and other workers by policy design, education, and research. It may well be that the Parkinson phenotype is not the result of a single gene defect or of exposure to a single environmental toxin, but rather multiple potential combinations of genetic and environmental interactions. Ultimately the hope is that knowledge gained in studies such as this will allow clinicians to screen individuals for susceptibility genes, and advise them on specific environmental factors that need to be avoided in order to prevent the subsequent development of PD years later. [Description provided by NIOSH]
• Subjects:
  Insecticides Occupational Health Safety
• Keywords:
  Cell-biology Cell-function Cell-metabolism Cell-morphology Cellular-function Cellular-structures Pest-control Pesticide-industry Pesticide-residues Pesticides Pesticides-and-agricultural-chemicals

  More +
• ISSN:
  1098-1861
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 5 ; Wisconsin
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  20-24
• Volume:
  101
• Issue:
  5
• NIOSHTIC Number:
  nn:20029622
• Citation:
  WMJ 2002 Jan; 101(5):20-24
• Contact Point Address:
  Marshfield Medical Research Foundation, 1000 N Oak Ave, Marshfield, WI 54449
• Email:
  greenla@mfldclin.edu
• Federal Fiscal Year:
  2002
• Performing Organization:
  Marshfield Clinic Research Foundation
• Peer Reviewed:
  True
• Start Date:
  20010930
• Source Full Name:
  Wisconsin Medical Journal
• End Date:
  20040929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9af8a9a6953989e8996037a797f68c3b56736a62424948e0659af77cca261cfd9e82e0802e9b06a318300378365c96a23b59c34b32e719729fd87b143642f339
• Download URL:
  https://stacks.cdc.gov/view/cdc/190562/cdc_190562_DS1.pdf
• File Type:
  [PDF - 1.06 MB ]