Relations Among Early Postexposure Noise-Induced Threshold Shifts and Permanent Threshold Shifts in the Chinchilla

Details

• Personal Author:
  Ahroon WA ; Hamernik RP ; Patterson JH Jr. ; Qiu W ; Ahroon WA ; Hamernik RP ; Patterson JH Jr. ; Qiu W
• Description:
  Threshold shifts (TS) were measured at various times following a wide variety of noise exposures on over 900 chinchillas. An analysis of postexposure TS measures and noise-induced permanent threshold shift (PTS) showed that, across audiometric test frequency, there was a consistent relation between these variables of the form PTS (dB) = alpha(e(TS/beta) - 1), where, for a given test frequency, alpha (dB) and beta (dB) are constants. TSs were measured immediately following exposure (TS0), 24 h after exposure (TS24), and at several intermediate times in order to estimate the maximum TS (TSmax). Correlation between TS and PTS at the various test frequencies was highest for TS24. An analysis of the 90th-percentile PTS showed a linear growth of PTS with TS24 of approximately 0.7 dB PTS/dB TS24. These data provide some support, in the chinchilla model, for a variation of the three postulates originally presented by Kryter et al. [J. Acoust. Soc. Am. 39, 451 (1966)]. Specifically: (i) TS24 is a consistent measure of the effects of a traumatic noise exposure. (ii) All exposures that produce a given TS24 will be equally hazardous. (iii) Noise-induced PTS in the most susceptible animals, following many years of exposure, is approximately equal to (0.7)TS24 measured after an 8-h exposure to the same noise. [Description provided by NIOSH]
• Subjects:
  Animals Ear Hearing Loss Hearing Loss, Noise-Induced Laboratories Noise Occupational Health Safety Sense Organs
• Keywords:
  Animal-studies Cell-damage Ear-disorders Hearing-loss Laboratory-animals Noise-exposure Noise-induced-hearing-loss
• ISSN:
  0001-4966
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Pages in Document:
  320-326
• Volume:
  111
• Issue:
  1
• NIOSHTIC Number:
  nn:20029506
• Citation:
  J Acoust Soc Am 2002 Jan; 111(1)(Pt 1):320-326
• Contact Point Address:
  Auditory Research Laboratory, State University of New York, Plattsburgh 12901
• Email:
  roger.hamernik@plattsburgh.edu
• Federal Fiscal Year:
  2002
• Performing Organization:
  Plattsburgh State University, New York
• Peer Reviewed:
  True
• Part Number:
  1
• Start Date:
  19860301
• Source Full Name:
  Journal of the Acoustical Society of America
• End Date:
  20130514
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:f821224888c76db6bab5468f5e101d054bbc3f23bc24c64d3c9f9e3335bab7deaabb5fcaffa413fb8125a5942cc1d0649ac4aca5a2bdf66b6f5cf8272e373303
• Download URL:
  https://stacks.cdc.gov/view/cdc/190464/cdc_190464_DS1.pdf
• File Type:
  [PDF - 484.12 KB ]