Systemic Inflammatory Mediators Contribute to Widespread Effects in Work-Related Musculoskeletal Disorders

Details

• Personal Author:
  Barbe MF ; Barr AE ; Clark BD
• Description:
  Recent studies in a rat model have indicated that the pathophysiological mechanisms underlying development of work-related musculoskeletal disorders (WMSDs) include widespread inflammation and subsequent fibrosis at high levels of repetition and force. A systemic inflammatory component may affect tissues not directly involved in task performance, thereby contributing to widespread and puzzling symptoms that are often characteristic of patients with WMSDs. Description provided by NIOSH
• Subjects:
  • Animals
  • Cumulative Trauma Disorders
  • Ergonomics
  • Laboratories
  • Musculoskeletal Diseases
  • Musculoskeletal System
  • Occupational Health
  • Safety
• Keywords:
  • Animal-studies
  • Laboratory-animals
  • Muscular-disorders
  • Musculoskeletal-system-disorders
  • Muscle-tissue
  • Muscle-function
  • Repetitive-work
  • Ergonomics
  • Cumulative-trauma
  • Cumulative-trauma-disorders
• ISSN:
  0091-6331
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  135-142
• Volume:
  32
• Issue:
  4
• NIOSHTIC Number:
  nn:20028927
• Citation:
  Exerc Sport Sci Rev 2004 Oct; 32(4):135-142
• Contact Point Address:
  Department of Work Environment, University of Massachusetts Lowell, Lowell, Massachusetts 01854
• Federal Fiscal Year:
  2005
• NORA Priority Area:
  Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
• Performing Organization:
  Temple University
• Peer Reviewed:
  True
• Start Date:
  20000601
• Source Full Name:
  Exercise and Sport Sciences Reviews
• End Date:
  20120731
• Download URL:
  https://stacks.cdc.gov/view/cdc/190017/cdc_190017_DS1.pdf
• File Type:
  [PDF - 592.52 KB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3f8665f93be5eebfb1219e7b1fa207516adddf340cf305ddded99b0d74e80ae2101193aef5772633bfb5ff37208ea0202ef86635732659482539c0f891f81f1d