Systemic Inflammatory Mediators Contribute to Widespread Effects in Work-Related Musculoskeletal Disorders

Details

• Personal Author:
  Barbe MF ; Barr AE ; Clark BD
• Description:
  Recent studies in a rat model have indicated that the pathophysiological mechanisms underlying development of work-related musculoskeletal disorders (WMSDs) include widespread inflammation and subsequent fibrosis at high levels of repetition and force. A systemic inflammatory component may affect tissues not directly involved in task performance, thereby contributing to widespread and puzzling symptoms that are often characteristic of patients with WMSDs. [Description provided by NIOSH]
• Subjects:
  Animals Cumulative Trauma Disorders Ergonomics Laboratories Musculoskeletal Diseases Musculoskeletal System Occupational Health Safety
• Keywords:
  Animal-studies Cumulative-trauma Cumulative-trauma-disorders Laboratory-animals Muscle-function Muscle-tissue Muscular-disorders Musculoskeletal-system-disorders Repetitive-work
• ISSN:
  0091-6331
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  135-142
• Volume:
  32
• Issue:
  4
• NIOSHTIC Number:
  nn:20028927
• Citation:
  Exerc Sport Sci Rev 2004 Oct; 32(4):135-142
• Contact Point Address:
  Department of Work Environment, University of Massachusetts Lowell, Lowell, Massachusetts 01854
• Federal Fiscal Year:
  2005
• NORA Priority Area:
  Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
• Performing Organization:
  Temple University
• Peer Reviewed:
  True
• Start Date:
  20000601
• Source Full Name:
  Exercise and Sport Sciences Reviews
• End Date:
  20120731
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:3f8665f93be5eebfb1219e7b1fa207516adddf340cf305ddded99b0d74e80ae2101193aef5772633bfb5ff37208ea0202ef86635732659482539c0f891f81f1d
• Download URL:
  https://stacks.cdc.gov/view/cdc/190017/cdc_190017_DS1.pdf
• File Type:
  [PDF - 592.52 KB ]