Needs and Opportunities for Research in Hypersensitivity Pneumonitis

Details

• Personal Author:
  Cormier YF ; Fan LL ; Fink, Jordan N. ; Frank TJ ; Kreiss, Kathleen ; Kunkel S ; Lynch D ; Ortega, Hector G. ; Quirce S ; Reynolds HY ; Rose C ; Schleimer RP ; Schuyler MR ; Selman M ; Trout, Douglas B. ; Yoshizawa Y
• Description:
  Hypersensitivity pneumonitis (HP) develops after inhalation of many different environmental antigens, causing variable clinical symptoms that often make diagnosis uncertain. The prevalence of HP is higher than recognized, especially its chronic form. Mechanisms of disease are still incompletely known. Strategies to improve detection and diagnosis are needed, and treatment options, principally avoidance, are limited. A workshop recommended: a population-based study to more accurately document the incidence and prevalence of HP; better classification of disease stages, including natural history; evaluation of diagnostic tests and biomarkers used to detect disease; better correlation of computerized tomography lung imaging and pathologic changes; more study of inflammatory and immune mechanisms; and improvement of animal models that are more relevant for human disease. [Description provided by NIOSH]
• Subjects:
  Antigens Biomarkers Diagnosis Hypersensitivity Occupational Diseases Occupational Health Safety
• Keywords:
  Diagnostic-tests Disease-prevention Diseases Hypersensitivity Pneumonitis Occupational-diseases
• ISSN:
  1073-449X
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies ; DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  171
• Issue:
  7
• NIOSHTIC Number:
  nn:20028890
• Citation:
  Am J Respir Crit Care Med 2005 Apr; 171(7):792-798
• Contact Point Address:
  Herbert Y. Reynolds, M.D., DLD/NHLBI, Two Rockledge Center, 6701 Rockledge Drive, Bethesda, MD 20892-7952
• Email:
  reynoldh@mail.nih.gov
• Federal Fiscal Year:
  2005
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Respiratory and Critical Care Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:eba856ad4ee664b7cbf7bd566e9c69da53ecbd5c4719332642e08812d8dd64574db76079ac71d03cd5e2ab8752bc9c417fe421ed57bd808277a9d3421a05593e
• Download URL:
  https://stacks.cdc.gov/view/cdc/189986/cdc_189986_DS1.pdf
• File Type:
  [PDF - 82.14 KB ]