High-Resolution CT in Silicosis: Correlation with Radiographic Findings and Functional Impairment

Details

• Personal Author:
  Cavalcanti dos Santos Antão V ; Kavakama J ; Muller NL ; Pinheiro GA ; Terra-Filho M
• Description:
  To assess high-resolution computed tomography (HRCT) findings in silicosis and to better define the role of HRCT in early detection of parenchymal abnormalities in silica-exposed workers. Forty-one stone carvers were evaluated with chest radiographs (CR), HRCT, and pulmonary function tests (PFT). Inter-reader agreement was calculated using the kappa statistic (k). Correlation between radiographic and HRCT profusion scores and PFT was assessed using the Spearman correlation coefficient. The most common HRCT findings were branching centrilobular structures, seen in 28/41 workers (68.3%). Nodules consistent with silicosis were detected in 53.7% workers on CR and in 56.1% workers on HRCT. Inter-reader agreement for diagnosis of silicosis was better on HRCT (k = 0.84) than on CR (k = 0.54). Small opacity profusion on HRCT correlated inversely with total lung capacity and FVC%. Profusion of opacities on HRCT correlates with functional impairment. The presence of branching centrilobular structures may be helpful in early recognition of silicosis. [Description provided by NIOSH]
• Subjects:
  Aluminum Silicates Environmental Monitoring Occupational Exposure Occupational Health Radiation Radiography Respiratory Function Tests Safety Silicon Dioxide Silicosis
• Keywords:
  Author Keywords: Silicosis Exposure-assessment Exposure-levels HRCT ILO Reading Kappa Statistics Occupational-exposure Pulmonary-function-tests Radiographic-analysis Silica-dusts Silicates Stone Carving Surveillance Worker-health Workers

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• ISSN:
  0363-8715
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  350-356
• Volume:
  29
• Issue:
  3
• NIOSHTIC Number:
  nn:20028884
• Citation:
  J Comput Assist Tomogr 2005 May-Jun; 29(3):350-356
• Contact Point Address:
  Dr. Vinicius C.S. Antao, 132 Bakers Drive, Morgantown, WV 26505
• Email:
  VAntao@cdc.gov
• Federal Fiscal Year:
  2005
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Computer Assisted Tomography
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:1e1d294102d7925adf10d97bd37df6351cfa49656f18a99d9dd2e7c248a1e83e8b58d6363a7871e95fcecae002bc0de255decb0a40cd28f0266efc0dc6319b35
• Download URL:
  https://stacks.cdc.gov/view/cdc/189980/cdc_189980_DS1.pdf
• File Type:
  [PDF - 4.68 MB ]