Sleep Duration and Oxidative Stress: The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) Study

Details

• Personal Author:
  Andrew, Michael E. ; Browne RW ; Burchfiel CM ; Charles LE ; Fekedulegn D ; McCanlies E ; Violanti JM
• Description:
  Our objective was to investigate the cross-sectional association between sleep duration and biomarkers of oxidative stress (glutathione (GSH), glutathione peroxidase (GSH-Px), vitamin C, thiobarbituric acid reactive substances (TBARS), and trolox equivalent antioxidant capacity (TEAC)) among police officers. Standardized techniques were used to analyze biomarkers in fasting blood specimens. Mean levels of biomarkers were compared across levels of sleep duration (0-4.9, 5.0-6.9, = 7.0 hours) using ANOVA. Officers' (women=44; men=69) mean age was 39.6 years. Positive trends were observed across sleep categories with mean levels of GSH and vitamin C only among women (p trend=0.156 and 0.022 respectively), with attenuation after risk-factor adjustment. Positive trends were observed for vitamin C among older officers (p trend=0.018) but not younger. No associations were observed between sleep duration and biomarkers among men. Longer sleep duration is associated with higher levels of vitamin C among policewomen and older officers. Additional studies are warranted. [Description provided by NIOSH]
• Subjects:
  Age Factors Biological Factors Biomarkers Hematologic Tests Occupational Health Oxidants Periodicity Safety Sleep Sleep Initiation And Maintenance Disorders
• Keywords:
  Age-factors Biological-effects Biological-factors Biological-function Biological-rhythms Biological-systems Blood-analysis Oxidative-metabolism Oxidative-processes Sleep-deprivation Sleep-disorders Statistical-analysis Stress

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• ISSN:
  1874-6209
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2 ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  15-25
• Volume:
  1
• NIOSHTIC Number:
  nn:20034491
• Citation:
  Open Sleep J 2008 Mar; 1:15-25
• Contact Point Address:
  Luenda E. Charles, National Institute for Occupational Safety and Health, HELD/BEB, MailStop L-4050, 1095 Willowdale Rd., Morgantown, WV 26505-2888
• Email:
  lcharles@cdc.gov
• Federal Fiscal Year:
  2008
• NORA Priority Area:
  Services ; Public Safety
• Peer Reviewed:
  True
• Source Full Name:
  The Open Sleep Journal
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2f72827f3781be4fb890834bbc402f74c3a086ed8ea52c940ccedffa6e2aacf748accb78de44c0780a735baf614669516ae8e9405642fdf1d43fcc0609e12dd2
• Download URL:
  https://stacks.cdc.gov/view/cdc/189651/cdc_189651_DS1.pdf
• File Type:
  [PDF - 167.72 KB ]