Ah Receptor: Xenobiotic Response Meets Inflammation

Details

• Personal Author:
  Ma Q
• Description:
  AhR mediates a broad range of biological responses to environmental chemicals, including suppression of immune functions. In this issue of Blood, Lawrence and colleagues demonstrate that AhR is responsible for the anti-inflammatory activity of new antiallergic drug candidates, likely by blocking dendritic-cell function to generate proinflammatory T-helper cells. [Description provided by NIOSH]
• Subjects:
  Chemistry Environmental Exposure Environmental Pollution Hypersensitivity Immune System Occupational Health Safety
• Keywords:
  Allergic-reactions Biological-effects Biological-monitoring Biological-systems Cell-biology Cell-function Cellular-function Cellular-reactions Chemical-hypersensitivity Chemical-properties Drug-receptor Drugs Environmental-exposure Environmental-hazards Immune-system Immunochemistry

  More +
• ISSN:
  0006-4971
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  112
• Issue:
  4
• NIOSHTIC Number:
  nn:20034328
• Citation:
  Blood 2008 Aug; 112(4):928-929
• Contact Point Address:
  Health Effects Laboratory Division, CDC National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV, 26505
• CAS Registry Number:
  2,3,7,8-Tetrachlorodibenzo-p-dioxin (CAS RN 1746-01-6)
• Federal Fiscal Year:
  2008
• Peer Reviewed:
  False
• Source Full Name:
  Blood
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6314a8bb14fd6e069c116f383d4efdb890446bf22aa7e8e04744c72ab988298ca51735b1bb23aba423aa97e5d901e6907355c31ca242e934c5ae2f4a8967a733
• Download URL:
  https://stacks.cdc.gov/view/cdc/189576/cdc_189576_DS1.pdf
• File Type:
  [PDF - 163.01 KB ]