A Micro-Hemolysis Assay for Monitoring Mineral Dusts

Details

• Personal Author:
  Bolsaitis P ; Rainey L ; Razzaboni BL ; Vallyathan V ; Wallace WE Jr.
• Description:
  The hemolytic activity of milligram-sized mineral dust samples from coal mines collected in personal dust samplers were measured by a modified Harington assay method which increases the sensitivity of the technique. Measurements were conducted on a large number of samples from different mines characterized for gravimetric quartz content and the relative bulk concentration of common contaminants (Al,Ca,Fe). The results of these measurements were compared to the hemolytic activity of pure quartz and of mineral samples obtained from roof-bolter dust boxes of two coal mines. No correlation could be established between hemolytic activity and the compositional variables tested. The results suggest that the distribution of minerals among individual particles and the surface characteristics of particles, rather than the bulk concentration, determine the hemolytic activity of respirable mine dusts. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Coal Coal Mining Dust Mining Occupational Health Particulate Matter Quartz Safety Silicon Compounds Silicon Dioxide

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• Keywords:
  Airborne-dusts Airborne-particles Coal-dust Coal-mining Dust-analysis Dust-exposure Dust-particles Dust-sampling Mineral-dusts Mining-industry Particulate-dust Quartz-dust Silica-dusts Silicon-compounds

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• ISBN:
  9780873350983
• Publisher:
  Society for Mining, Metallurgy, and Exploration, Inc.
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  Colorado ; OSHA Region 3 ; OSHA Region 8 ; Pennsylvania ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  111-115
• NIOSHTIC Number:
  nn:20034317
• Citation:
  Respirable dust in the mineral industries, proceedings of the 3rd symposium on respirable dust in the mineral industries, October 17-19, 1990, Pittsburgh, Pennsylvania. Frantz RL, Ramani RV, eds. Littleton, CO: Society for Mining, Metallurgy, and Exploration, Inc., 1991 Jan; :111-115
• CAS Registry Number:
  Quartz (SiO2) (CAS RN 14808-60-7)
• Editor(s):
  Frantz RL; Ramani RV
• Federal Fiscal Year:
  1991
• Peer Reviewed:
  False
• Source Full Name:
  Respirable dust in the mineral industries, proceedings of the 3rd symposium on respirable dust in the mineral industries, October 17-19, 1990, Pittsburgh, Pennsylvania
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:04ba9c31c04d261919aecc8b467982cff5e5ce4718647075c575507315fe9c40e3ed2816e2d8fc888586ebbe13c94284f60f085bb5f8b1561a8ab04d879deb72
• Download URL:
  https://stacks.cdc.gov/view/cdc/189565/cdc_189565_DS1.pdf
• File Type:
  [PDF - 2.70 MB ]